62053-94-5Relevant academic research and scientific papers
The Use of Grignard Reagents in Carbohydrate Synthesis. The Synthesis of Branched-chain Deoxy Sugars and Their Anomerizations
Kawana, Masajiro,Koresawa, Tetsuo,Kuzuhara, Hiroyoshi
, p. 1095 - 1100 (2007/10/02)
The reactions of methyl 5-O-benzyl-2-O- and -3-O-tosyl-β-D-ribofuranosides with methylmagnesium iodide gave, in one-step, 2-deoxy-3-C- and 3-deoxy-2-C-methyl branched-chain sugars, respectively. These sugars were anomerized with Grignard reagents; the thermodynamically more stable anomers were converted preferentially into the respective less stable anomers.
