620536-30-3Relevant academic research and scientific papers
High yield [125I]iodide-labeling of iodinated carboranes by palladium-catalyzed isotopic exchange
Winberg, Karl Johan,Barberà, Gemma,Eriksson, Ludvig,Teixidor, Francesc,Tolmachev, Vladimir,Vi?as, Clara,Sj?berg, Stefan
, p. 188 - 192 (2003)
We have recently shown the feasibility of palladium-catalyzed isotopic exchange between [125I]iodide and 2-iodo-para-carborane. In this work we have modified the methodology and extended its application to a wider range of iodinated carboranes. Thus, by using Herrmann's catalyst in toluene at 100 °C, 2-I-p-, 3-I- o -, 9-I-o -, 9-I- m -carborane, 1-phenyl-3-I- o -carborane and 1,2-diphenyl-3-I-o -carborane have been radiolabeled with 125 iodine in high to excellent yields.
