62056-53-5Relevant academic research and scientific papers
Application of Diphenylphosphinic Carboxylic Mixed Anhydrides to Peptide Synthesis.
Ramage, Robert,Hopton, David,Parrott, Maxwell J.,Richardson, Reginald S.,Kenner, George W.,Moore, Geoffrey A.
, p. 461 - 470 (2007/10/02)
Diphenylphosphinic carboxylic mixed anhydrides formed in situ from Nα-protected amino acids and diphenylphosphinic chloride have been critically evaluated in peptide synthesis.Wherever possible, 32.4 MHz 31P n.m.r. spectroscopy has been employed to follow the rates of both mixed anhydride formation and aminolysis.
Phosphorylation with N-Phosphorylpyrazoles, IV. - Phosphorylations of Carboxylic Acids
Regitz, Manfred,Weise, Gisela,Felcht, Utz
, p. 1232 - 1238 (2007/10/02)
Reaction of 1-phosphorylpyrazole (1a) with the carboxylic acids 5a-f leads initially to the mixed anhydrides 6a-f, which then transform the 1-H-pyrazole 3, arising from phosphoryl group transfer, into the 1-acylpyrazoles 7a-f.Carboxylic acid phosphinic acid anhydrides 6b, c and g-k are also formed on reaction of the phosphinic acid chloride 9 and carboxylic acids in the presence of triethylamine; acylation of 3 with 6b, c, i and k is described.
