62062-75-3

Upstream product

• 530-53-0 deoxyvasicinone 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1341211-43-5 C₁₈H₁₅N₃O₂ 
• 1341211-42-4 C₁₈H₁₅N₃O₂ 
• 1341211-45-7 C₁₉H₁₅N₃O₃ 
• 1341211-47-9 C₁₉H₁₅N₃O₃ 
• 1341211-46-8 C₁₉H₁₅N₃O₃ 
• 1341211-44-6 C₁₈H₁₅N₃O₂ 
• 143051-82-5 3-(Phenyl-hydrazonomethyl)-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one; hydrochloride 
• 98260-34-5 3-(2-formamidophenyl)-1,2,3,9-tetrahydropyrrolo<2,1-b>quinazolin-9-one 
• 142834-66-0 3-(2-aminophenyl)-1,2,3,9-tetrahydropyrrolo<2,1-b>quinazolin-9-one 
• 142834-63-7 3-(Phenyl-hydrazonomethyl)-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one 

Relevant academic research and scientific papers

Nitrogen Bridgehead Compounds. Part 35. Structures of α-Formyl-2,3-polymethylene-3,4-dihydroquinazolin-4-ones

The structures of the title compounds bearing a five-, six- or seven-membered A ring have been investigated by uv and 1H and 13C nmr spectroscopy.The imine-enol-enamine (I-II-III) tautomerism of these compounds depends greatly on the ring size.A significant solvent-dependence is observed only for the five-membered-ring compounds 1 and 2, which in ethanolic solution exist predominantly in the imine form I, and in chloroform solution in the enol form II.The compounds with a six-membered A ring, 3 and 4, are mainly in the enamine form III.On protonation, 3 and 4 change into the E and Z isomeric mixture of the enol tautomer II.The seven-membered-ring compound 5 is a mixture of the imine I and the enamine III tautomers.

Some reactions of α-hydroxymethylene- and α-dimethylaminomethylene-2,3-polymethylene-3,4-dihydroquinazolin-4-ones

By the reaction of α-hydroxymethylene- and α-dimethylaminomethylene-2,3-polymethylene-3,4-dihydroquinazolin-4-ones with acid anhydrides and primary and secondary amines, the corresponding α-acyloxymethylene- and α-mono(di)-substituted aminomethylene-2,3-polymethylene-3,4-dihydroquinazolin-4-ones have been synthesized. The addition of hydrocyanic acid (from acetone cyanohydrin) to the double bond of the methylene group of the α-hydroxymethylene- and α-dimethylaminomethylene-2,3-trimethylene-3,4-dihydroquinazolin-4-ones has led to α-[cyano-(hydroxy)methyl1]- and α-[cyano(dimethylamino)methyl]-2,3-trimethylene-3,4-dihydroquinazolin-4-ones.