142834-66-0

Basic information

• Product Name: 3-(2-aminophenyl)-1,2,3,9-tetrahydropyrrolo<2,1-b>quinazolin-9-one
• Synonyms: 3-(2-aminophenyl)-1,2,3,9-tetrahydropyrrolo<2,1-b>quinazolin-9-one
• CAS NO: 142834-66-0
• Molecular Weight: 277.326
• Mol File: 142834-66-0.mol

Chemical Properties

• CAS DataBase Reference: 3-(2-aminophenyl)-1,2,3,9-tetrahydropyrrolo<2,1-b>quinazolin-9-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-aminophenyl)-1,2,3,9-tetrahydropyrrolo<2,1-b>quinazolin-9-one(142834-66-0)
• EPA Substance Registry System: 3-(2-aminophenyl)-1,2,3,9-tetrahydropyrrolo<2,1-b>quinazolin-9-one(142834-66-0)

Safety Data

• Hazardous Substances Data: 142834-66-0(Hazardous Substances Data)

Upstream product

• 142834-64-8 spiro<3H>indoleninpyrroloquinazolinone 
• 98260-34-5 3-(2-formamidophenyl)-1,2,3,9-tetrahydropyrrolo<2,1-b>quinazolin-9-one 
• 98260-32-3 2-chloro-3-<2-(indol-3-yl)ethyl>-4(3H)-quinazolinone 
• 607-69-2 2-chloro-4(3H)-quinazolinone 
• 55982-76-8 tryptophyl bromide 
• 143051-82-5 3-(Phenyl-hydrazonomethyl)-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one; hydrochloride 
• 142834-63-7 3-(Phenyl-hydrazonomethyl)-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one 
• 100-63-0 phenylhydrazine 
• 62062-75-3 3-<(dimethylamino)methylene>tetrahydropyrrolo<2,1-b>quinazolinone 

Downstream Products

• 113010-10-9 3-<2-(dimethylamino)phenyl>-2,3-dihydropyrrolo<2,1-b>quinazolin-9(1H)-one; Vasicolinone 

Relevant articles and documents

An Alternative Total Synthesis of Rutaecarpine and Vasicolinone Alkaloids

Rutaecarpine (6) and vasicolinone (9) alkaloids were alternatively prepared by Fischer indolization of 3-(phenylhydrazonomethyl)pyrroloquinazolinone (4) under thermal and acidic conditions, respectively.

A SHORT SYNTHESIS OF RUTECARPINE AND/OR VASICOLINONE FROM 2-CHLORO-3-(INDOL-3-YL)ETHYLQUINAZOLIN-4(3H)-ONE: EVIDENCE FOR THE PARTICIPATION OF THE SPIRO INTERMEDIATE

A new route to rutecarpine and/or vasicolinone from 2-chloro-4-quinazolone through an acid catalyzed cyclization of 2-chloro-3-indolylethylquinazolin-4-one has been developed and the mechanism of the cyclization reaction clarified.