6207-31-4Relevant academic research and scientific papers
1,3-Dipolar cycloaddition in the synthesis of novel isoxazoline/pyrazole derivatives bearing 1,2,3-triazoles moiety
Zeng, Yongming,Liu, Fangming
, p. 696 - 702 (2013)
1,3-Dipolar cycloaddition of α,β-unsaturated ketones bearing 1,2,3-triazole moiety with nitrile oxides and sydnones obtained a series of novel 3,4,5-trisubstituted isoxazolines (5a-h) and 1,3,4-trisubstituted pyrazoles (7a-h) with different active pharmacophores in a single molecular scaffold. The structure of the target compounds was confirmed on the basis of IR, 1H NMR, mass spectral, elemental analysis, and X-ray crystallographic analysis.
2H-1,2,3-Triazole-chalcones as novel cytotoxic agents against prostate cancer
Carneiro, José Walkimar M.,Filho, Eclair Venturini,Fiorot, Rodolfo G.,Freitas, Maria Clara R.,Greco, Sandro J.,Guimar?es, Anderson R. A.,Loureiro, Laiza B.,Muri, Estela M. F.,Pess?a, Jaqueline C.,Pinheiro, Erick M. C.,Pinheiro, Sergio,Rocha-Brito, Karin J. P.,Rotamiro, Karina M.,Silva Junior, Carlos M. D.
, (2020)
Prostate cancer is an important cause of death in the male population and for which there is no satisfactory chemotherapy. Herein a new series of chalcone hybrids containing 2H-1,2,3-triazole core as the ring B has been synthesized and evaluated in vitro
Synthesis, docking, machine learning and antiproliferative activity of the 6-ferrocene/heterocycle-2-aminopyrimidine and 5-ferrocene-1H-Pyrazole derivatives obtained by microwave-assisted Atwal reaction as potential anticancer agents
Antoniazi, Mariana K.,Filho, Eclair Venturini,Greco, Sandro J.,Loureiro, Laiza B.,Pessoa, Claudia,Pina, Jorge W. S.,Pinheiro, Carlos B.,Ribeiro, Marcos A.,Taranto, Alex G.,Guimar?es, Celina J.,de Oliveira, Fátima C. E.
supporting information, (2021/07/13)
A simple and fast methodology under microwave irradiation for the synthesis of 2-aminopyrimidine and pyrazole derivatives using Atwal reaction is reported. After the optimization of the reaction conditions, eight 2-aminolpyrimidines containing ferrocene a
Synthesis and activity of 1,2,3-triazolyl-chalcones against the fungus colletotrichum lindemuthianum
Pess?a, Jaqueline Cavalcanti,Azevedo, Roberto Faria,Mota, Suellen Finamor,Pinheiro, Sergio,Muri, Estela Maris Freitas,de Souza, Elaine Aparecida,Oliveira, Denilson Ferreira
, p. 787 - 796 (2018/09/26)
Background: Anthracnose, caused by the fungus Colletotrichum lindemuthianum, is one of the most important diseases that affect common beans. As some chalcones and triazoles are active cores against fungi, 1,2,3-triazolyl-chalcone hybrids could present mor
Synthesis of 1,5-benzodiazepine derivatives containing 1,2,3-triazole moiety via 1,3-dipolar cycloaddition reaction
Dong, Zhi-Qiang,Shi, Hai,Chen, Sen-Lin,Chen, Hong-Xiang,Jiang, Wei-Bin,Liu, Fang-Ming,Hong, Mei-Lin
, p. 1844 - 1848 (2015/01/09)
A series of 1,5-benzodiazepine derivatives were synthesized by the reaction of 1,5-benzodiazepine containing 1,2,3-triazole moiety with benzohydroximinoyl chlorides at room temperature. The structural identities of these novel compounds were confirmed on
Synthesis and spectral characterization of some novel thiazolyl-pyrazoline derivatives containing 1,2,3-triazole moiety
Shi, Hai,Liu, Fang-Ming,Shen, Song-Wei
scheme or table, p. 263 - 270 (2011/04/24)
Chemical Equation Presented A series of novel 3-aryl-5-(2-aryl-1,2,3- triazol-4-yl)-1-(4-aryl-2-thiazoyl)-pyrazolines 6a-6r were synthesized using 2-aryl-4-formyl-1,2,3-triazoles 1a,b as the starting materials. Thus, reacting 1a,b with 1-arylethanones 2a-
