62070-75-1Relevant articles and documents
Water Mediated Direct Thioamidation of Aldehydes at Room Temperature
Gupta, Ankush,Vankar, Jigarkumar K.,Jadav, Jaydeepbhai P.,Gururaja, Guddeangadi N.
, p. 2410 - 2420 (2022/02/23)
A mild, greener approach toward thioamide synthesis has been developed. Its unique features include water-mediated reaction with no input energy, additives, or catalysts as well. The presented protocol is attractive with readily available starting materials and the use of different array amines, along with a scaled-up method. Biologically active molecules such as thionicotinamide and thioisonicotinamide can be synthesized from this procedure.