6208-36-2

Upstream product

• 98-86-2 acetophenone 
• 5351-69-9 4-Phenyl-3-thiosemicarbazide 
• 103-72-0 phenyl isothiocyanate 
• 13466-30-3 (1-phenylethylidene)hydrazine 
• 1122-62-9 2-acetylpyridine 
• 302-01-2 hydrazine 

Downstream Products

• 128680-30-8 Cu(C₆H₅C(CH₃)NNC(S)NHC₆H₅)(CH₃COO) 
• 1202879-02-4 Ru(CO)(As(C₆H₅)3)2(C₆H₅CCH₃N₂CSNHC₆H₅) 
• 1357348-62-9 Pd(κ3-C4,N3,S-acetophenone-N-phenylthiosemicarbazonato) 
• 189172-66-5 Ga(CH₃)2[(CH₃)(C₆H₅)CNNC(S)NC₆H₅]Ga(CH₃)2 
• 128702-48-7 Cd(C₆H₅C(CH₃)NNHC(S)NHC₆H₅)Cl₂*H₂O 
• 128680-31-9 Zn(C₆H₅C(CH₃)NNC(S)NHC₆H₅)2 
• 128680-32-0 Hg(C₆H₅C(CH₃)NNHC(S)NHC₆H₅)Cl₂*H₂O 
• 128680-29-5 Co(C₆H₅C(CH₃)NNC(S)NHC₆H₅)2 
• 22177-08-8 2-phenylamino-5-phenyl-6H-1,3,4-thiadiazine 
• 6254-84-8 [4-oxo-3-phenyl-2-(1-phenyl-ethylidenehydrazono)-thiazolidin-5-yl]-acetic acid 

Relevant academic research and scientific papers

Synthesis, crystal structure and biological evaluation of a main group seven-coordinated bismuth(III) complex with 2-acetylpyridine N 4-phenylthiosemicarbazone

Up to now, bismuth(III) complexes with thiosemicarbazones have been comparatively rare. Here, a main group seven-coordinated bismuth(III) complex [Bi(L)(NO3)2(CH3CH2OH)] (1) (HL = 2-acetylpyridine N(4)-phenylthiosemicarbazone) has been synthesized and characterized by elemental analysis, IR, 1H NMR and single-crystal X-ray diffraction studies. The cytotoxicity data suggest that 1 exhibits higher in vitro antiproliferative activity in four human cancer cells tested. Its possible apoptotic mechanism has been evaluated in HepG2 cells. Compound 1 promotes a dose-dependent apoptosis in HepG2 cells and the apoptosis is associated with an increase in intracellular reactive oxygen species (ROS) production and reduction of mitochondrial membrane potential (MMP).

Organometallic ruthenium(II) complexes containing NS donor Schiff bases: Synthesis, structure, electrochemistry, DNA/BSA binding, DNA cleavage, radical scavenging and antibacterial activities

Four new cyclopentadienylruthenium(II)-acetophenone-4(N)-substituted thiosemi-carbazone complexes, with the general formula [Ru(?5-C5H5)(H-Aptsc)PPh3].Cl (1), [Ru(?5-C5H5)(H-Apmt

Impact and correlation of p: K a and dn electrons of some selected thiosemicarbazone Schiff base metal Co, Ni, Cu complexes: A study of electrochemical behavior, excitation and optical energies

The electron-transfer and coordination mechanism of Schiff bases with metal ions, correlation of the electrochemical and optical properties for their potential applications in various fields of chemistry and biochemistry are underexplored. Thus, detailed

Synthesis, characterization, and anticancer activity of a series of ketone-N4-substituted thiosemicarbazones and their ruthenium(II) arene complexes

A series of ketone-N4-substituted thiosemicarbazone (TSC) compounds (L1-L9) and their corresponding [(η6-p-cymene)Ru II(TSC)Cl]+/0 complexes (1-9) were synthesized and characterized by NMR, IR, elemental analysis, and HR-ESI-mass spectrometry. The molecular structures of L4, L9, 1-6, and 9 were determined by single-crystal X-ray diffraction analysis. The compounds were further evaluated for their in vitro antiproliferative activities against the SGC-7901 human gastric cancer, BEL-7404 human liver cancer, and HEK-293T noncancerous cell lines. Furthermore, the interactions of the compounds with DNA were followed by electrophoretic mobility spectrometry studies.

Ruthenium(II) mediated C-H activation of substituted acetophenone thiosemicarbazones: Synthesis, structural characterization, luminescence and electrochemical properties

Treatment of [RuHCl(CO)(AsPh3)3] with 4′-substituted acetophenone thiosemicarbazone derivatives in methanol under reflux afford a series of air stable new ruthenium(II) cyclometalated complexes containing thiosemicarbazone of general

One-pot and catalyst-free synthesis of thiosemicarbazones via multicomponent coupling reactions

A novel and efficient procedure for the synthesis of thiosemicarbazones has been achieved via a multicomponent and catalyst-free reaction of phenyl or p-chlorophenyl isothiocyanate, hydrazine, and aldehydes or ketones. The method afforded 20 thiosemicarba

Spectroscopic, thermal and electrochemical studies on some nickel(II) thiosemicarbazone complexes

Several complexes of thiosemicarbazone derivatives with Ni(II) have been prepared. Structural investigation of the ligands and their complexes has been made based on elemental analysis, magnetic moment, spectral (UV-Vis, i.r., 1H NMR, ms), and

Synthesis and antibacterial activity of pyridyl thioureas and arylthiosemicarbazones

[N-(2-pyridyl)-N'-(4-(un) substituted] thioureas and (substitutedaryl)thiosemicarbazones were synthesised and evaluated for their antibacterial activity. All aryl thiosemicarbazones showed good activity against Aeromonas hydrophilia and Salmonella typhimuriurn. But none of the pyridyl thioureas showed any prominent activity against tested bacteria.