62083-20-9

Upstream product

• 108-94-1 cyclohexanone 
• 123-72-8 butyraldehyde 
• 106-98-9 1-butylene 
• 108-95-2 phenol 
• 529-28-2 4-iodoanisol 

Relevant academic research and scientific papers

Pd-catalyzed cross-electrophile Coupling/C-H alkylation reaction enabled by a mediator generatedviaC(sp3)-H activation

Transition-metal-catalyzed cross-electrophile C(sp2)-(sp3) coupling and C-H alkylation reactions represent two efficient methods for the incorporation of an alkyl group into aromatic rings. Herein, we report a Pd-catalyzed cascade cross-electrophile coupling and C-H alkylation reaction of 2-iodo-alkoxylarenes with alkyl chlorides. Methoxy and benzyloxy groups, which are ubiquitous functional groups and common protecting groups, were utilized as crucial mediatorsviaprimary or secondary C(sp3)-H activation. The reaction provides an innovative and convenient access for the synthesis of alkylated phenol derivatives, which are widely found in bioactive compounds and organic functional materials.

Dinitroalkyl aromatics polymerization retarders or inhibitors and methods for making and for using same

A vinyl monomer inhibitor systems is disclosed which includes 2,6-dinitro-4-alkylated phenols and mixtures of 2,6-dinitro-4-alkylated phenols and 2,4-dinitro-6-alkylated phenols as well as vinyl monomer stabilized composition including an effective amount of the inhibitor systems. A method for the preparation and use is also disclosed where phenol is first alkylated under conditions that afford predominately monoalkylated phenols having a high para alkylation preference, followed by nitration of the alkylated phenols to form a dinitrated, monoalkylated product.

Facile Synthesis of 2,6-Dialkylphenols by Cross-Aromatization of Cyclohexanones with Aldehydes Catalyzed by Zirconocene Complexes

2,6-Dialkylphenols, which are difficult to prepare by conventional methods, have been conveniently synthesized in one step via zirconocene-catalyzed cross-aromatization of cyclohexanones with aldehydes.