62085-75-0

Basic information

• Product Name: Cyclohexanone, 2,6-bis(2-furanylmethylene)-, (E,E)-
• CAS NO: 62085-75-0
• Molecular Formula: C16H14O3
• Molecular Weight: 254.285
• Mol File: 62085-75-0.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: Cyclohexanone, 2,6-bis(2-furanylmethylene)-, (E,E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanone, 2,6-bis(2-furanylmethylene)-, (E,E)-(62085-75-0)
• EPA Substance Registry System: Cyclohexanone, 2,6-bis(2-furanylmethylene)-, (E,E)-(62085-75-0)

Safety Data

• Hazardous Substances Data: 62085-75-0(Hazardous Substances Data)

Upstream product

• 98-01-1 furfural 
• 108-93-0 cyclohexanol 
• 108-94-1 cyclohexanone 
• 56-23-5 tetrachloromethane 
• 64-17-5 ethanol 
• 7732-18-5 water 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 95164-74-2 optically inactive 2-((Ξ)-furfurylidene)-6-[[2]furyl-(2-oxo-cyclohexyl)-methyl]-cyclohexanone 

Downstream Products

• 95164-74-2 optically inactive 2-((Ξ)-furfurylidene)-6-[[2]furyl-(2-oxo-cyclohexyl)-methyl]-cyclohexanone 
• 122388-23-2 2,6-bis-[[2]furyl-(2-oxo-cyclohexyl)-methyl]-cyclohexanone 

Relevant articles and documents

Reactions Of Ruran Aldehydes 4. Oxidation-Reduction Reactions Of Furfural with Monohydric Alcohols

Furfural oxidizes aliphatic and alicyclic alcohols at 70-100 deg C under the action of sodium alcoholate to aldehydes and ketones, and then participates in a crotonate condensation.At 0-10 deg C the alcohol is not oxidized but the adduct with alkoxide ion is oxidized to form an alkyl furoate.

Bi-functional modified-phosphate catalyzed the synthesis of α-α′-(EE)-bis(benzylidene)-cycloalkanones: Microwave versus conventional-heating

The impregnation of hydroxyapatite (HAP) by NaNO3 leads to a modified-hydroxyapatite which has a bi-functional acid-base property. Sodium-modified-hydroxyapatite (Na-HAP) efficiently catalyzed the cross-aldol condensation of arylaldehydes and cycloketones to afford α-α′- (EE)-bis(benzylidene)-cycloalkanones in good yields under microwave irradiation. Moreover, the methodology described in this paper provides a very easy and efficient synthesis carried out in water as the greenest available solvent under conventional heating. A comparison study between these two different modes of heating was investigated. The catalyst was easily recovered and efficiently re-used.

A facile synthesis of α,α′-(EE)-bis(benzylidene)-cycloalkanones and their antitubercular evaluations

An economical and facile synthesis of α,α′-(EE)-bis(benzylidene)-cycloalkanones was achieved by the reaction of cycloalkanones with different aromatic aldehydes using ethanolic KOH in good yields. Few of the selected compounds were reduced with NaBH4 to the respective α,α′-(EE)-bis(benzylidene)-cycloalkanols. All these compounds and our earlier synthesized cyclohexyl phenyl methanols were evaluated for their antitubercular, antifungal and antibacterial activities. Several compounds displayed moderate antitubercular activity with MIC = 12.5-1.56 μg/mL. However, none of the compounds displayed any significant antifungal activity.