62085-91-0

Upstream product

• 100-52-7 benzaldehyde 
• 29943-42-8 Tetrahydro-4H-pyran-4-one 
• 108-97-4 4-pyrone 

Downstream Products

• 101894-03-5 3,5-dibenzyl-pyran-4-one 
• 69539-78-2 4-(4,5-Dihydro-thiazol-2-ylamino)-3,5-bis-[1-phenyl-meth-(E)-ylidene]-tetrahydro-pyran-4-ol 
• 69539-79-3 C₂₂H₂₀N₂OS 
• 62513-32-0 7-(Z)-benzylidene-3-phenyl-2-propyl-2,3,3a,4,6,7-hexahydro-pyrano[4,3-c]pyrazole 
• 83319-93-1 7-(Z)-benzylidene-3-phenyl-1-propyl-1,4,6,7-tetrahydro-pyrano[4,3-c]pyrazole 
• 62513-34-2 2-[3-(4-Methyl-piperazin-1-yl)-propyl]-3-phenyl-7-[1-phenyl-meth-(Z)-ylidene]-2,3,3a,4,6,7-hexahydro-pyrano[4,3-c]pyrazole 

Relevant academic research and scientific papers

Application of monocarbonyl curcumin compound in preparation of medicine for preventing and treating periodontitis

The invention belongs to the technical field of medicines, and particularly relates to application of a specific monocarbonyl curcumin analogue in preparation of a medicine for preventing and treating periodontitis. Experiments prove that the monocarbonyl curcumin analogues not only can play a better anti-oxidation protection role by activating an Nrf2/HO-1 signal channel, but also can play an anti-inflammatory role by inhibiting release of inflammatory factors TNF alpha and IL1-beta, so that the monocarbonyl curcumin analogues have a remarkable prevention and treatment effect on rat periodontitis, have good potential value and significance for prevention and treatment of periodontitis, and have a good research and development prospect.

Synthesis and X-ray crystallographic analysis of a bis(arylmethylidene) pyranone structure

The exocyclic olefinic bonds and their E-E configuration in a bis(arylmethylidene)pyranone system are confirmed for the first time by X-ray crystallography of the 3,5-dibenzylidene-tetrahydropyran-4-one derivative.

A highly efficient method for solvent-free synthesis of bisarylmethylidenes of pyranones and thiopyranones

A remarkable efficient double crossed aldol condensation of heterocyclic ketones with a variety of aromatic aldehydes is described at room temperature in the presence of magnesium bromide ethyl etherate, triethylamine, and methanol under solvent-free cond

Synthesis and antiinflammatory activity of hexahydrothiopyrano[4,3-c]pyrazoles and related analogues

A series of novel hexahydrothiopyrano[4,3-c]pyrazoles and related analogues were prepared and tested for antiinflammatory activity by using the mouse active Arthus reaction and the delayed hypersensitivity skin reaction in guinea pigs as primary screens.

Syntheses and a Conformational Study of Certain Selected 3-Oxa-7-azabicyclononan-9-ones. Single-Crystal X-ray Diffraction Analysis of 6,8-Bis(2-chlorophenyl)-3-oxa-7-azabicyclononan-9-one.

Isomers of 2,4,6,8-tetraphenyl-3-oxa-7-azabicyclononan-9-ones, 6,8-bis(2-chlorophenyl)-3-oxa-7-azabicyclononan-9-one, and N-benzyl-3-oxa-7-azabicyclononan-9-one have been prepared by Mannich-type cyclocondensations with appropiate tet