62101-57-9

Usage

Uses

Used in Organic Synthesis:
2,4-Imidazolidinedione, 3-(4-nitrophenyl)is used as a reagent in organic synthesis for its ability to undergo nucleophilic substitution reactions, which is crucial for the formation of various complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2,4-Imidazolidinedione, 3-(4-nitrophenyl)is used as an intermediate in the synthesis of various drugs, contributing to the development of new medicinal compounds.
Used in Agrochemical Production:
Similarly, in the agrochemical sector, 2,4-Imidazolidinedione, 3-(4-nitrophenyl)- is employed as an intermediate, playing a key role in the synthesis of pesticides and other agricultural chemicals to enhance crop protection and yield.

Upstream product

• 67513-13-7 5-(4-nitro-phenyl)-hydantoic acid 
• 100-28-7 4-Nitrophenyl isocyanate 
• 56-40-6 glycine 
• 590-28-3 potassium cyanate 
• 17329-87-2 2-chloro-N-(4-nitro-phenyl)-acetamide 
• 636-98-6 p-nitrobenzene iodide 
• 461-72-3 2,4-imidazolidinedione 

Downstream Products

• 625094-32-8 3-(4-aminophenyl)-imidazolidine-2,4-dione 

Relevant academic research and scientific papers

Cu-catalyzed N-3-Arylation of Hydantoins Using Diaryliodonium Salts

A general Cu-catalyzed, regioselective method for the N-3-arylation of hydantoins is described. The protocol utilizes aryl(trimethoxyphenyl)iodonium tosylate as the arylating agent in the presence of triethylamine and a catalytic amount of a simple Cu-salt. The method is compatible with structurally diverse hydantoins and operates well with neutral aryl groups or aryl groups bearing weakly donating/withdrawing elements. It is also applicable for the rapid diversification of pharmaceutically relevant hydantoins.

SUBSTITUENT EFFECTS ON HYDROLYTIC STABILITY AND HERBICIDAL ACTIVITY OF 3-ARYLIMIDAZOLIDINE-2,4-DIONES

Twenty-one derivatives of imidazolidine-2,4-dione have been prepared by reactions of substituted amino acids with aryl isocyanates in aqueous medium.Pre- and post-emergent herbicidal activities of all the compounds have been tested, and stability of five derivatives has been followed in aqueous medium within the pH range from 7.6 to 13.0.The highest pre-emergent herbicidal activity has been found with the derivatives XI-XVI which inhibit the growth of most indicator plants at the doses of 1.6 kg/ha.The derivatives studied are relatively stable in aqueous medium, the hydrolysis half-life of the compound XI being 9 days at pH 8.

STUDIES ON HYDANTOIN. PART 2. SUBSTITUENT EFFECTS IN 3-ARYLHYDANTOINS ON THE FORMATION OF ARYL ISOCYANATE IONS USING THE MASS-ANALYSED ION KINETIC ENERGY-DIRECT ANALYSIS OF DAUGHTER IONS

The unimolecular reaction of seven 3-arylhydantoins, relatively slow fragmentation in the free drift region, has been investigated by analysis of the mass-analysed ion kinetic energy (m.i.k.e.) spectrum using direct analysis of daughter ions (d.a.d.i.).Ar