62103-45-1

Upstream product

• 62103-44-0 2,5-di-O-benzyl-3,4-O-isopropylidene-L-rhamnose diethyl dithioacetal 
• 100-39-0 benzyl bromide 
• 62103-49-5 3,4-O-isopropylidene-L-rhamnose diethyl dithioacetal 

Downstream Products

• 62103-46-2 methyl 2,5-di-O-benzyl-6-deoxy-α-L-mannofuranoside 
• 108223-93-4 methyl 2,5-di-O-benzyl-6-deoxy-3-C-methyl-α-L-mannofuranoside 
• 108223-92-3 methyl 2,5-di-O-benzyl-6-deoxy-α-L-mannofuranosid-3-ulose 

Relevant academic research and scientific papers

New sugars from antigenic lipopolysaccharides of bacteria: identification and synthesis of 3-O-[(R)-1-carboxyethyl]-L-rhamnose, an acidic component of Shigella dysenteriae type 5 lipopolysaccharide.

A new acidic sugar, 3-O-[(R)-1-carboxyethyl]-L-rhamnose (1), has been identified as a constituent of the O-antigenic lipopolysaccharide of Sh. dysenteriae type 5. The structure of 1 has been established by physico-chemical methods and by synthesis. Alkylation of methyl 2,5-di-O-benzyl-alpha-L-rhamnofuranoside (6) with (S)- or (R)-2-chloropropionic acids, followed by removal of the protecting groups, afforded 3-O-[(R)-1-carboxyethyl]-L-rhamnose (9) and 3-O-[(S)-1-carboxyethyl]-L-rhamnose (10), respectively. The properties of 1 coincide with those of 9.