62135-01-7Relevant articles and documents
Iron Catalyzed Isomerization of α-Alkyl Styrenes to Access Trisubstituted Alkenes
Xu, Songgen,Liu, Guixia,Huang, Zheng
, p. 585 - 589 (2021/02/01)
Stereoselective isomerization of α-alkyl styrenes is accomplished using a new iron catalyst supported by phosphine-pyridine-oxazoline (PPO) ligand. The protocol provides an atom-efficient and operationally simple approach to trisubstituted alkenes in high
PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS
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Paragraph 000443-000444, (2015/09/28)
The present invention relates to compositions comprising 2-phenyl linear alkene benzenes or 2-phenyl linear alkene benzene sulfonates or 2-phenyl linear alkylbenzenes or 2-phenyl linear alkylbenzene sulfonates; where the benzene ring is optionally substituted with one or more groups designated R *, where R * is defined herein and to methods for making the same. This invention also relates to compositions, methods of making, use of, and articles of manufacuture comprising 2-ethoxylated hydroxymethylphenyl linear alkyl benzenes or 2-propoxylated hydroxymethylphenyl linear alkyl benzenes.
Pd-catalyzed selective tandem arylation-alkylation of 1,1-dihalo-1-alkenes with aryl- and alkylzinc derivatives to produce α-alkyl-substituted styrene derivatives
Shi, Ji-cheng,Negishi, Ei-ichi
, p. 518 - 524 (2007/10/03)
Trans -selective monoarylation of 1,1-dibromo- and 1,1-dichloro-1-alkenes (1) can be achieved in >80% yields and in ≥98-99% stereoselectivity with arylzinc bromides in the presence of a catalytic amount of Cl2Pd(DPEphos) or Cl2Pd(dppb), the former permitting cleaner and higher yielding reactions. Although THF is a generally satisfactory solvent, ether and toluene are superior to THF in some cases. The second substitution of (Z)-α-bromostyrenes (3) with alkylzincs in the presence of 2 mol% of Pd(t Bu3P)2 proceeds to give the corresponding 2 in >90% yields and in ≥98-99% stereoselectivity. Although somewhat less satisfactory, the use of Cl2Pd(DPEphos) permits a one-pot tandem arylation-alkylation.
Vinylic Organoboranes. 11. A Highly Stereospecific and Regiospecific Synthesis of Trisubstituted Alkenes via Organoboranes
Brown, Herbert C.,Bhat, Narayan G.
, p. 6009 - 6013 (2007/10/02)
A highly stereospecific synthesis of trisubstituted alkenes using (E)- and (Z)-2-(1-substituted-1-alkenyl)-1,3,2-dioxaborinanes is presented. (E)-2-(1-Substituted-1-alkenyl)-1,3,2-dioxaborinanes (1), as described previously, readily react with organolithium or Grignard reagents in diethyl ether at -78 deg C to form the corresponding "ate" complexes.Treatment of these "ate" complexes with iodine in methanol induces the migration of the alkyl group from boron to the adjacent carbon, followed by a base-induced deiodoboronation to afford stereodefined trisubstituted alkenes in good yields (50-82percent) and in excellent stereochemical purities (97percent).Similarly (Z)-2-(1-substituted-1-alkenyl)-1,3,2-dioxaborinanes (2), easily obtainable by a previous procedure, react with organolithium or Grignard reagents, followed by treatment with iodine and base, to produce the stereoisomeric trisubstituted alkenes in good yields (65-82percent) and in excellent isomeric purites (97percent).These two procedures provide a convenient route to any of the six possible trisubstituted alkenes, R1CH=CR2R3.
