62135-57-3Relevant academic research and scientific papers
Synthetic method 1, 2 and 4 - triazole compound
-
Paragraph 0070-0073, (2021/12/07)
The invention discloses 1. 2,4 - Triazole compound synthesis method belongs to the technical field of synthesis of triazole compounds. After the reaction is finished, the reaction is carried out under the heating condition, and the target product 1, 2 and
Method for electrochemically synthesizing 1, 2 and 4 - triazole compounds
-
Paragraph 0022-0037; 0038-0041, (2020/10/20)
The invention discloses a method of electrochemically synthesizing a 1, 2, 4-triazole compound. The method includes: dissolving a compound (I) and quaternary ammonium salt into acetonitrile, stirringat room temperature of 50 DEG C to obtain reaction liqui
Intramolecular electrochemical dehydrogenative N-N bond formation for the synthesis of 1,2,4-triazolo[1,5-a] pyridines
Li, Yong,Ye, Zenghui,Chen, Na,Chen, Zhenkun,Zhang, Fengzhi
supporting information, p. 4035 - 4039 (2019/08/07)
A metal- and oxidant-free intramolecular dehydrogenative N-N bond formation has been developed under mild and scalable electrolytic conditions. Various valuable 1,2,4-triazolo[1,5-a]pyridines were synthesized efficiently from the readily available N-(2-pyridyl)amidines. The reactions were conducted in a simple undivided cell under constant current conditions with nBu4NBr as both the redox mediator and the electrolyte. This protocol was applied to the efficient synthesis of key intermediates for anti-diabetic compounds.
PhI(OAc) 2 -Mediated Regioselective Synthesis of 5-Guanidino-1,2,4-thiadiazoles and 1,2,4-Triazolo[1,5- a ]pyridines via Oxidative N-S and N-N Bond Formation
Krishna, Palakodety Radha,Mangarao, Nakka,Nagaraju, Tumula,Sridhar, Balasubramanian
, p. 3600 - 3610 (2019/09/30)
An effective and expeditious approach for the construction of biologically important 5-guanidino-1,2,4-thiadiazole and 1,2,4-triazolo[1,5- a ]pyridine derivatives has been developed. This new protocol involves the phenyliodine(III) diacetate [PhI(OAc) su
Heterogeneous Copper(I)-Catalyzed Cascade Addition-Oxidative Cyclization of Nitriles with 2-Aminopyridines or Amidines: Efficient and Practical Synthesis of 1,2,4-Triazoles
Xia, Jianhui,Huang, Xue,Cai, Mingzhong
, p. 2014 - 2022 (2019/04/26)
The heterogeneous cascade addition-oxidative cyclization of nitriles with 2-aminopyridines or amidines was achieved in 1,2-dichlorobenzene or DMSO at 120-130 °C by using a 1,10-phenanthroline-functionalized MCM-41-supported copper(I) complex [Phen-MCM-41-
Facile synthesis of 1,2,4-triazoles via a copper-catalyzed tandem addition-oxidative cyclization
Ueda, Satoshi,Nagasawa, Hideko
supporting information; experimental part, p. 15080 - 15081 (2010/01/16)
A simple one-step synthesis of 1,2,4-triazole derivatives is provided by a copper-catalyzed oxidative coupling reaction under an atmosphere of air. The process should consist of sequential N-C and N-N bond-forming copper-catalyzed oxidative coupling reactions. Starting materials and the copper catalyst are readily available and inexpensive. A wide range of functional groups are tolerated to achieve chemical diversity.
Imidazopyridine derivatives as angiotensin II receptor antagonists, pharmaceuticals, and treatment of hypertension therewith
-
, (2008/06/13)
Imidazo-fused iso- and heterocycles, process for their preparation, compositions containing them and their useA compound of the formula STR1 in which the symbols have the following meaning: X is a monocyclic radical having 3,4 or 5 ring atoms,R 1,R 2,R 3,
The Reaction of 2-Nitrosopyridine with Nitrile Oxides: First Synthesis of 1,2,4-Triazolopyridine 1,3-Di-N-oxides
Gallos, John K.,Lioumi, Maria I.,Lekka, Anastasia N.
, p. 287 - 288 (2007/10/02)
Reactions of 2-nitrosopyridine with nitrile oxides afford either the novel title compounds or the corresponding 1,2,4-triazolopyridine 3-oxides
Formation and Pyrolysis of 1-(2'-Pyridyl)-5-aryltetrazoles
Rao, P. Jayaprasad,Reddy, K. Kondal
, p. 117 - 120 (2007/10/02)
A number of 1-(2'-pyridyl)-5-aryltetrazoles (Va-k) have been obtained by the reaction of 2-aroylamidopyridines (III) with phosphorus pentachloride and azidolysis of the resulting imidoyl chlorides.The products obtained on pyrolysis of 1-(2'-pyridyl)-5-ary
