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Furan, 2,5-bis(chloromethyl)is a chemical compound with the molecular formula C6H6Cl2O and a molecular weight of 169.02 g/mol. It is a derivative of furan, a heterocyclic compound with a five-membered ring containing four carbon atoms and one oxygen atom. The 2,5-bis(chloromethyl) substitution results in a highly reactive and potentially toxic compound.

6214-02-4

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6214-02-4 Usage

Uses

Used in Organic Synthesis:
Furan, 2,5-bis(chloromethyl)is used as a chemical intermediate in organic synthesis for the production of various organic compounds.
Used in Polymer Production:
Furan, 2,5-bis(chloromethyl)is used as a chemical intermediate for the production of polymers, contributing to the formation of polymer chains.
Used in Resin Production:
Furan, 2,5-bis(chloromethyl)is used as a chemical intermediate in the production of resins, which are used in various applications such as coatings, adhesives, and composite materials.
Used in Pharmaceutical Production:
Furan, 2,5-bis(chloromethyl)is used as a chemical intermediate in the production of pharmaceuticals, aiding in the synthesis of various drug compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 6214-02-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,1 and 4 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 6214-02:
(6*6)+(5*2)+(4*1)+(3*4)+(2*0)+(1*2)=64
64 % 10 = 4
So 6214-02-4 is a valid CAS Registry Number.

6214-02-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,5-bis(chloromethyl)furan

1.2 Other means of identification

Product number -
Other names 2,5-bis-chloromethyl-furan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6214-02-4 SDS

6214-02-4Relevant academic research and scientific papers

Facile Preparation of High Molecular Weight, Highly Conductive Poly(2,5-furylene vinylene)

Jen, Kwan-Yue,Jow, T. R.,Elsenbaumer, Ronald L.

, p. 1113 - 1115 (1987)

High molecular weight, freestanding films of poly(2,5-furylene vinylene) (PFV) are readily prepared via a water soluble precursor polymer, are electrochemically reversibly donor and acceptor dopable, and reach conductivities as high as 36 S/cm on acceptor doping.

Synthesis, antimicrobial activity, and ion transportation investigation of four new [1 + 1] condensed furan and thiophene-based cycloheterophane amides

?zcan, Hafize,Erku?, Betül,Zaim, ?mer

, (2020/02/18)

Four new macrocyclic compounds with thiophene (L1 and L2) and furan (L3 and L4) rings were synthesized and characterized by IR, 1H NMR, 13C NMR, and Q-TOF spectral data. Macrocyclic amides (L1, L2, L3, and L4) were tested for ion transportation with Na+ and K+ ions, and also, antimicrobial activities were investigated against the Gram-negative Escherichia coli ATCC 25922, Gram-positive Staphylococcus aureus ATCC 25923, Gram-negative Listeria monocytogenes ATCC 19115, Gram-negative Salmonella typhimurium ATCC 14028, Bacillus cereus bacteria, and Candida albicans ATCC 10231 for all amides.

Furfurylamines from biomass: Transaminase catalysed upgrading of furfurals

Dunbabin, Alice,Subrizi, Fabiana,Ward, John M.,Sheppard, Tom D.,Hailes, Helen C.

, p. 397 - 404 (2017/01/29)

Furfural is recognised as an attractive platform molecule for the production of solvents, plastics, resins and fuel additives. Furfurylamines have many applications as monomers in biopolymer synthesis and for the preparation of pharmacologically active compounds, although preparation via traditional synthetic routes is not straightforward due to by-product formation and sensitivity of the furan ring to reductive conditions. In this work transaminases (TAms) have been investigated as a mild sustainable method for the amination of furfural and derivatives to access furfurylamines. Preliminary screening with a recently reported colorimetric assay highlighted that a range of furfurals were readily accepted by several transaminases and the use of different amine donors was then investigated. Multistep synthetic routes were required to synthesise furfurylamine derivatives for use as analytical standards, highlighting the benefits of using a one step biocatalytic route. To demonstrate the potential of using TAms for the production of furfurals, the amination of selected compounds was then investigated on a preparative scale.

(POP)Rh pincer hydride complexes: Unusual reactivity and selectivity in oxidative addition and olefin insertion reactions

Haibach, Michael C.,Wang, David Y.,Emge, Thomas J.,Krogh-Jespersen, Karsten,Goldman, Alan S.

, p. 3683 - 3692 (2013/11/19)

We report on the synthesis and reactivity of rhodium complexes featuring bulky, neutral pincer ligands with a "POP" coordinating motif, tBuxanPOP, iPrxanPOP, and tBufurPOP ( tBuxanPOP = 4,5-bis(di-tert-butylphosphino)-9,9-dimethyl-9H-xanthene; iPrxanPOP = 4,5-bis(diisopropylphosphino)-9,9-dimethyl-9H-xanthene; tBufurPOP = 2,5-bis((di-tert-butylphosphino)methyl)furan). The (POP)Rh complexes described in this work are, in general, more reactive than their (PNP)Rh and (PCP)Rh analogues, which allows for the generation of several new species under relatively mild conditions. Thus, monomeric (POP)RhCl complexes oxidatively add H2 to form (POP)Rh(H)2Cl, from which the coordinatively unsaturated hydride complexes (POP)Rh(H) 2+ and (tBuxanPOP)Rh(H) can be obtained. In the case of the new ligand tBufurPOP, a major kinetic product of the reaction with H2 is, surprisingly, the trans dihydride, i.e. trans-(tBufurPOP)Rh(H)2Cl; this is most likely attributable to reversible decoordination of one of the pincer coordinating groups, followed by addition of H2 to a highly reactive three-coordinate species. Ethylene is hydrogenated by (tBuxanPOP) Rh(H)2+ at 25 °C, but propylene is not, even at elevated temperatures. Ethylene undergoes insertion into the Rh-H bond of ( tBuxanPOP)RhH; this reaction is reversible, allowing for an experimental determination of the equilibrium constant for this hydrometalation. The less bulky iPrxanPOP ligand affords a dihydride complex which functions as a modestly active alkane dehydrogenation catalyst, the first such example for a cationic pincer complex of any metal.

Studies on Organolanthanide Complexes. Part 55. Synthesis of Furan-bridged Bis(cyclopentadienyl) Lanthanide and Yttrium Chlorides, and Ligand and Metal Tunnig of Reactivity of Organolanthanide Hydrides (in situ)

Qian, Changtago,Zhu, Dunming

, p. 1599 - 1604 (2007/10/02)

Four new complexes (Ln = Y, Yb, Sm or Nd) were synthesised by using furan-bridged bis(cyclopentadienes) as ancillary ligands and characterized by elemental analyses, mass, IR and 1H NMR spectroscopy.The spectra indicate that these complexes are chloride-bridged dimers and the two furan-bridged cyclopentadienyl rings co-ordinate to each metal in a chelating fashion with intramolecular co-ordination between the oxygen atom and the metal.The effects of the bridging chain and the central metal upon the reactivity of organolanthanide hydrides generated in situ form the -NaH system were investigated.The reactivity can be tuned not only by varying the ligands but also by taking advantage of the lanthanide contraction.The ligand tunability varies for different reactions.More reactive organolanthanide hydride species (in situ) can be obtained by both 'ligand tuning' and 'metal tuning', i.e. by selecting the appropriate ancillary ligands and the early lanthanide metals.

Synthesis and Characterization of some 1,4,8,11,15,18,22,25-Octa(alkoxymethyl)phthalocyanines; a New Series of Discotic Liquid Crystals

Cammidge, Andrew N.,Cook, Michael J.,Harrison, Kenneth J.,McKeown, Neil B.

, p. 3053 - 3058 (2007/10/02)

A series of 3,6-bis(alkoxymethyl)phthalonitriles, prepared via Diels-Alder reactions of 2,5-bis(alkoxymethyl)furans with fumaronitrile, have been converted into the corresponding phthalocyanines.Zn(II) and Cu(II) derivatives of 1,4,8,11,15,18,22,25-octa(heptyloxymethyl)phthalocyanine were also prepared.Examples of the macrocycles were characterised using 1H NMR spectrometry and optical spectroscopy.Those bearing straight chains aggregate in solutions of chloroform and toluene.The octa(butoxymethyl)phthalocyanine and its longer chain homologues exhibit a discotic liquid crystalline phase.Compounds containing branched sidechains are liquid crystals at room temperature.

New Tetraheterocyclic Macrocycles Containing Triazole, Pyrazole, Pyridine, and/or Furan Subunits. Synthesis and Cation Binding Properties

Tarrago, Georges,Marzin, Claude,Najimi, Ouafa,Pellegrin, Valdo

, p. 420 - 425 (2007/10/02)

Ten new tetraheterocyclic macrocyclic ligands 2-4 in the porphyrinogen series were prepared.Their structures differ from 1 in (1) the type of junction between heterocycles (NCH2C or CCH2C), (2) the donor nature of the complexation sites, (3) the five- or six-membered geometry of the included heterocycles, and (4) their symmetry.The capabilities of 2-4 for extraction and transport of alkali metal and NH4+ cations were less than those of 1.The rigid dipyrazole ditriazole macrocycles 3 extract Na+ selectively, whereas the more flexible dipyrazole monotriazole monopyridine macrocycles 2 have the best transport selectivity for Na+.

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