6214-02-4

Basic information

• Product Name: Furan, 2,5-bis(chloromethyl)-
• Synonyms: 2,5-bis-chloromethyl-furan;2,5-Bis-chlormethyl-furan;Furan,2,5-bis(chloromethyl)
• CAS NO: 6214-02-4
• Molecular Formula: C6H6Cl2O
• Molecular Weight: 165.019
• Mol File: 6214-02-4.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Furan, 2,5-bis(chloromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Furan, 2,5-bis(chloromethyl)-(6214-02-4)
• EPA Substance Registry System: Furan, 2,5-bis(chloromethyl)-(6214-02-4)

Safety Data

• Hazardous Substances Data: 6214-02-4(Hazardous Substances Data)

Usage

General Description

"Furan, 2,5-bis(chloromethyl)-" is a chemical compound with the molecular formula C6H6Cl2O and a molecular weight of 169.02 g/mol. It is a derivative of furan, a heterocyclic compound with a five-membered ring containing four carbon atoms and one oxygen atom. The 2,5-bis(chloromethyl) substitution results in a highly reactive and potentially toxic compound that is used in organic synthesis and as a chemical intermediate in the production of polymers, resins, and pharmaceuticals. Exposure to this compound should be limited and appropriate safety measures should be employed due to its potential health hazards.

Upstream product

• 617-88-9 2-Chloromethylfuran 
• 50-00-0 formaldehyd 
• 67-47-0 5-hydroxymethyl-2-furfuraldehyde 
• 98-00-0 (2-furyl)methyl alcohol 
• 1883-75-6 2,5-bis-(hydroxymethyl)furan 

Downstream Products

• 25252-05-5 2,5-Bis-piperidinomethyl-furan 
• 94167-82-5 1,1'-(furan-2,5-diyl)bis(N,N-dimethylmethylamine) hydrochloride 
• 109476-93-9 2,5-bis(N,N-diethylaminomethyl)furan 
• 690996-96-4 [(MeC₄H₂OCH₂)Co(pyridine)(diphenyl glyoxime)2] 
• 690996-95-3 [(MeC₄H₂OCH₂)Co(pyridine)(dimethyl glyoxime)2] 
• 1469745-32-1 C₂₂H₄₂OP₂ 
• 2213-51-6 (furan-2,5-diyl) dimethanamine 
• 100504-33-4 1,9-dithia[2](2,5)furano[2](1,1')ferrocenophane 
• 25553-57-5 3³,7⁴-diethyl-3⁴,7³-dimethyl-1,5(2,5)-difurana-3,7(2,5)-dipyrrola-cyclooctaphane-1⁽²⁾,3⁽⁴⁾,6,8-tetraene 
• 109643-81-4 2,5-bis-triethylammoniomethyl-furan; diiodide 
• 109697-36-1 2,5-bis-[(diethyl-methyl-ammonio)-methyl]-furan; diiodide 
• 107662-70-4 2,5-bis-trimethylammoniomethyl-furan; diiodide 
• 110424-51-6 2,5-bis-(1-methyl-piperidinium-1-ylmethyl)-furan; diiodide 

Relevant articles and documents

Facile Preparation of High Molecular Weight, Highly Conductive Poly(2,5-furylene vinylene)

High molecular weight, freestanding films of poly(2,5-furylene vinylene) (PFV) are readily prepared via a water soluble precursor polymer, are electrochemically reversibly donor and acceptor dopable, and reach conductivities as high as 36 S/cm on acceptor doping.

Furfurylamines from biomass: Transaminase catalysed upgrading of furfurals

Furfural is recognised as an attractive platform molecule for the production of solvents, plastics, resins and fuel additives. Furfurylamines have many applications as monomers in biopolymer synthesis and for the preparation of pharmacologically active compounds, although preparation via traditional synthetic routes is not straightforward due to by-product formation and sensitivity of the furan ring to reductive conditions. In this work transaminases (TAms) have been investigated as a mild sustainable method for the amination of furfural and derivatives to access furfurylamines. Preliminary screening with a recently reported colorimetric assay highlighted that a range of furfurals were readily accepted by several transaminases and the use of different amine donors was then investigated. Multistep synthetic routes were required to synthesise furfurylamine derivatives for use as analytical standards, highlighting the benefits of using a one step biocatalytic route. To demonstrate the potential of using TAms for the production of furfurals, the amination of selected compounds was then investigated on a preparative scale.

Studies on Organolanthanide Complexes. Part 55. Synthesis of Furan-bridged Bis(cyclopentadienyl) Lanthanide and Yttrium Chlorides, and Ligand and Metal Tunnig of Reactivity of Organolanthanide Hydrides (in situ)

Four new complexes (Ln = Y, Yb, Sm or Nd) were synthesised by using furan-bridged bis(cyclopentadienes) as ancillary ligands and characterized by elemental analyses, mass, IR and 1H NMR spectroscopy.The spectra indicate that these complexes are chloride-bridged dimers and the two furan-bridged cyclopentadienyl rings co-ordinate to each metal in a chelating fashion with intramolecular co-ordination between the oxygen atom and the metal.The effects of the bridging chain and the central metal upon the reactivity of organolanthanide hydrides generated in situ form the -NaH system were investigated.The reactivity can be tuned not only by varying the ligands but also by taking advantage of the lanthanide contraction.The ligand tunability varies for different reactions.More reactive organolanthanide hydride species (in situ) can be obtained by both 'ligand tuning' and 'metal tuning', i.e. by selecting the appropriate ancillary ligands and the early lanthanide metals.