62141-41-7Relevant academic research and scientific papers
Electrophilic cyanations. I. Synthesis of thiocyanato-heteroarenes and tosylheteroarenes from mercapto-heteroarenes using p-toluenesulfonyl cyanide
Miyashita, Akira,Nagasaki, Izuru,Kawano, Akiko,Suzuki, Yumiko,Iwamoto, Ken-Ichi,Higashino, Takeo
, p. 745 - 755 (2007/10/03)
Mercaptoheteroarenes (1) underwent electrophilic cyanation with p-toluenesulfonyl cyanide (TsCN) in THF in the presence of NaH to give the corresponding thiocyanatoheteroarenes (2) in moderate to good yields. In DMF, tosylheteroarenes (4) were formed by substitution with p-toluenesulfinate ion through thiocyanatoheteroarenes (2).
