62155-46-8Relevant academic research and scientific papers
Alkylpotassium-Catalyzed Benzylic C-H Alkylation of Alkylarenes with Alkenes
Sato, Io,Yamashita, Yasuhiro,Kobayashi, Shū
supporting information, p. 240 - 250 (2019/01/04)
Catalytic benzylic C-H alkylation reactions of alkylarenes with alkenes such as β-substituted styrenes and vinylsilanes have been achieved by utilizing alkylpotassium as a catalyst. Various substituted toluene derivatives can be alkylated under mild reaction conditions to afford the desired functionalized hydrocarbons in moderate to high yields.
Catalytic Direct-Type Addition Reactions of Alkylarenes with Imines and Alkenes
Yamashita, Yasuhiro,Suzuki, Hirotsugu,Sato, Io,Hirata, Tsubasa,Kobayashi, Shū
supporting information, p. 6896 - 6900 (2018/05/14)
Catalytic addition reactions of very weakly acidic nonactivated alkylarenes such as toluene and its derivatives were developed by using a strongly basic mixed catalyst system under mild reaction conditions. The addition reactions with imines and alkenes proceeded smoothly under proton-transfer conditions to afford the desired products in good to high yields, and high levels of regio- and stereoselectivity were achieved. It was also revealed that the asymmetric addition reaction of an alkylarene was possible.
