62168-26-7

Basic information

• Product Name: 1,1-dibromooctane
• Synonyms: octane, 1,1-dibromo-
• CAS NO: 62168-26-7
• Molecular Formula: C₈H₁₆Br₂
• Molecular Weight: 272.0206
• Mol File: 62168-26-7.mol

Chemical Properties

• Boiling Point: 246.3°C at 760 mmHg
• Flash Point: 112.6°C
• Density: 1.452g/cm³
• Vapor Pressure: 0.043mmHg at 25°C
• Refractive Index: 1.493
• CAS DataBase Reference: 1,1-dibromooctane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dibromooctane(62168-26-7)
• EPA Substance Registry System: 1,1-dibromooctane(62168-26-7)

Safety Data

• Hazardous Substances Data: 62168-26-7(Hazardous Substances Data)

Usage

Physical state

Colorless to light yellow liquid

Odor

Slightly sweet

Uses

a. Intermediate in organic synthesis
b. Production of pharmaceuticals and agrochemicals
c. Solvent
d. Manufacture of surfactants and specialty chemicals

Hazard classification

Classified as a hazardous substance

Health hazards

a. Potential for causing skin and eye irritation
b. Respiratory and central nervous system effects

Environmental impact

Toxic to aquatic organisms

Handling precautions

Should be handled with care to prevent environmental contamination and health risks

Upstream product

• 124-13-0 Octanal 
• 4282-40-0 1-Iodoheptane 
• 74-95-3 1,1-dibromomethane 
• 93215-67-9 octanal 1,3-dithiolane 
• 629-05-0 n-octyne 

Downstream Products

• 50816-19-8 8-bromooctanol 
• 1570511-23-7 (R)-1-(4-methoxyphenyl)octan-1-ol 
• 178670-96-7 1-Bromo-10-cyclohexyldecane 

Relevant articles and documents

A Biomimetic Synthesis of des -Hydroxy Paecilospirone

The carbon framework of des -hydroxy paecilospirone was rapidly synthesized using a biomimetic approach whereby an enol ether and an ortho -quinone methide (o- QM), each derived from the same lactone, were combined to arrive at the complete carbon skeleton of paecilospirone.

A mild synthesis of vinyl halides and gem-dihalides using triphenyl phosphite-halogen-based reagents

A new application of (PhO)3P-halogen-based reagents to the synthesis of vinyl halides and gem-dihalides is described. Vinyl halides were prepared in good to excellent yields from enolizable ketones, whereas aldehydes afforded the corresponding gem-dihalides. The halogenation proceeded smoothly under mild conditions.

Synthesis of bromoalkenes and alkylidene dibromides by reactions of carbonyl compounds with 2,4,4,6-tetrabromo-2,5-cyclohexadienone in the presence of triphenylphosphine

Reactions of aliphatic and aromatic aldehydes with the 2,4,4,6-tetrabromo-2,5-cyclohexadienone-triphenylphosphine complex result in formation of the corresponding geminal dibromides. Ketones react with the same complex to give vinyl bromides.

THE REACTION OF ETHANEDIYL S,S-ACETALS WITH HALOGENES

Cyclic thioacetals and thioketals (1,3-dithiolanes) are reported to react smoothly with halogens in a 1:1 molar ratio, at room temperature in anhydrous carbon tetrachloride.The mechanistic aspects of the reaction are considered and evidence is shown of the itermediacy of monocationic rather than the previously postulated dicatonic species in the cleavage reactions of 1,3-dithiolanes of aromatic ketones.

Preparation des α-monohalogenoalkyllithiums non fonctionnels

The preparation of very unstable α-monohaloalkyllithiums (carbenoids), potential electro- and nucleophiles, from easily accessible gem-halogenated alkanes, by halogen-lithium exchange at low temperatures is described.R-CHXLi type carbenoids (R aryl, H or CH3 ; X = Cl, Br) are obtained by bromine-lithium exchange in a THF-ether-pentane mixture at temperatures below -115 deg C.The α-silylated organolithiums Me3SiCXLiR (R = H, alkyl; X = Cl, Br) despite their greater stability, must be prepared at the same temperature; secondary reactions are limited by the use of an inverse addition of secondary butyllithium.CH2XLi an RCXLiMe carbenoids (R = H, CH3 ; X = Cl, Br) have to be prepared in the presence of one equivalent of lithium bromide in order to reduce the halogen-lithium carbenoid interaction which is responsible for their instability.