6220-48-0 Usage
Uses
Used in Pharmaceutical Industry:
2(1H)-Pyrimidinone, 4-(dimethylamino)(9CI) is used as a chemical building block for the synthesis of various pharmaceutical compounds. Its unique structure and functional groups make it a valuable component in the development of new drugs.
Used in Drug Development:
Due to its potential biological activity, 2(1H)-Pyrimidinone, 4-(dimethylamino)(9CI) is utilized in the research and development of new drugs. Its properties are being explored for possible applications in medicine, with the aim of discovering its therapeutic potential and contributing to advancements in healthcare.
Check Digit Verification of cas no
The CAS Registry Mumber 6220-48-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,2 and 0 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6220-48:
(6*6)+(5*2)+(4*2)+(3*0)+(2*4)+(1*8)=70
70 % 10 = 0
So 6220-48-0 is a valid CAS Registry Number.
InChI:InChI=1/C19H15NO5/c21-16(13-5-2-1-3-6-13)12-25-19(24)14-7-4-8-15(11-14)20-17(22)9-10-18(20)23/h1-8,11H,9-10,12H2
6220-48-0Relevant academic research and scientific papers
A one-pot, water compatible synthesis of pyrimidine nucleobases under plausible prebiotic conditions
Okamura, Hidenori,Becker, Sidney,Tiede, Niklas,Wiedemann, Stefan,Feldmann, Jonas,Carell, Thomas
supporting information, p. 1939 - 1942 (2019/05/02)
Herein, we report a new prebiotically plausible pathway towards a pyrimidine nucleobase in continuous manner. The route involves simultaneous methylation and carbamoylation of cyanoacetylene-derived α,β-unsaturated thioamide with N-methyl-N-nitrosourea (MNU) in aqueous media. This provides S-methylpyrimidinone in one-pot, which can be converted into a variety of 4-substituted pyrimidine nucleobases including cytosine and uracil.
