6220-48-0 Usage
General Description
2(1H)-Pyrimidinone, 4-(dimethylamino)- (9CI) is a chemical compound with the molecular formula C7H10N2O. It is also known by the alternate name 4-(dimethylamino)pyrimidin-2(1H)-one. 2(1H)-Pyrimidinone, 4-(dimethylamino)- (9CI) is a pyrimidine derivative with a dimethylamino group attached to the fourth carbon of the pyrimidine ring. It is commonly used in the pharmaceutical industry as a building block for the synthesis of various pharmaceutical compounds. Additionally, it exhibits potential biological activity and may have applications in the development of new drugs. 2(1H)-Pyrimidinone, 4-(dimethylamino)- (9CI) is of interest to researchers and scientists for its potential pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 6220-48-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,2 and 0 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6220-48:
(6*6)+(5*2)+(4*2)+(3*0)+(2*4)+(1*8)=70
70 % 10 = 0
So 6220-48-0 is a valid CAS Registry Number.
InChI:InChI=1/C19H15NO5/c21-16(13-5-2-1-3-6-13)12-25-19(24)14-7-4-8-15(11-14)20-17(22)9-10-18(20)23/h1-8,11H,9-10,12H2
6220-48-0Relevant articles and documents
A one-pot, water compatible synthesis of pyrimidine nucleobases under plausible prebiotic conditions
Okamura, Hidenori,Becker, Sidney,Tiede, Niklas,Wiedemann, Stefan,Feldmann, Jonas,Carell, Thomas
supporting information, p. 1939 - 1942 (2019/05/02)
Herein, we report a new prebiotically plausible pathway towards a pyrimidine nucleobase in continuous manner. The route involves simultaneous methylation and carbamoylation of cyanoacetylene-derived α,β-unsaturated thioamide with N-methyl-N-nitrosourea (MNU) in aqueous media. This provides S-methylpyrimidinone in one-pot, which can be converted into a variety of 4-substituted pyrimidine nucleobases including cytosine and uracil.
