6220-49-1 Usage
Structure
Pyrimidine derivative with a methyl group and a methylamino group attached to the 4th carbon atom
Usage
Intermediate in the synthesis of pharmaceuticals and agrochemicals
Biological and pharmacological activities
+ Inhibitor of dihydrofolate reductase, an enzyme involved in the production of DNA and RNA
+ Potential as an antimalarial and antitumor agent
Check Digit Verification of cas no
The CAS Registry Mumber 6220-49-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,2 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6220-49:
(6*6)+(5*2)+(4*2)+(3*0)+(2*4)+(1*9)=71
71 % 10 = 1
So 6220-49-1 is a valid CAS Registry Number.
6220-49-1Relevant academic research and scientific papers
Reactions with Dimethyl Carbonate, 5 Methylation of the Pyrimidine Bases of Nucleic Acids
Jansen, Helmut in de Wal,Lissel, Manfred
, p. 863 - 865 (2007/10/02)
The methylation of the pyrimidine bases of nucleic acids by dimethyl carbonate is described compared to dimethyl sulphate.The reaction needs higher temperature, a base and the help of 18-crown-6 and DMF as cosolvent. - Keywords: Dimethyl Carbonate, Methylations, Pyrimidine Bases of Nucleic Acids
