62203-32-1

Usage

Uses

Used in Coatings Industry:
PDM is used as a key component in the production of high-quality coatings, where its mechanical strength and chemical resistance enhance the durability and performance of the final product.
Used in Adhesives Industry:
In the adhesives industry, PDM serves as an essential ingredient, improving the bonding strength and stability of adhesives across different surfaces and under various conditions.
Used in Composites Manufacturing:
PDM is utilized as a critical constituent in composite materials, where it contributes to the overall strength, flexibility, and resistance to environmental factors, making the composites suitable for a wide range of applications.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, PDM plays a significant role in the synthesis of new drugs and drug delivery systems, capitalizing on its unique molecular structure to develop advanced therapeutic agents and improve drug efficacy and targeting.
Overall, PDM's versatility and properties make it an invaluable compound in the creation of advanced materials for diverse industrial and biomedical applications.

Upstream product

• 65-85-0 benzoic acid 
• 77-86-1 2-amino-2-hydroxymethyl-1,3-propanediol 

Downstream Products

• 100956-81-8 4,4-bis-acetoxymethyl-2-phenyl-4,5-dihydro-oxazole 
• 889893-47-4 (R)-4-hydroxymethyl-2-phenyl-4,5-dihydrooxazol-4-ylmethyl acetate 
• 889893-54-3 ethyl (S,E)-3-[4-(tert-butyldimethylsiloxymethyl)-2-phenyl-4,5-dihydrooxazol-4-yl]acrylate 
• 889893-55-4 ethyl (S)-3-[4-(tert-butyldimethylsiloxymethyl)-2-phenyl-4,5-dihydrooxazol-4-yl]-propionate 
• 889893-52-1 (R)-4-(tert-butyldimethylsiloxymethyl)-2-phenyl-4,5-dihydrooxazol-4-ylmethyl acetate 
• 889893-49-6 ethyl (R,E)-3-(4-acetoxymethyl-2-phenyl-4,5-dihydrooxazol-4-yl)acrylate 
• 889893-53-2 (S)-(-)-(4-(tert-butyldimethylsilyloxymethyl)-2-phenyl-4,5-dihydrooxazol-4-yl)methanol 
• 889893-56-5 methyl (S)-4-(2-ethoxycarbonylethyl)-2-phenyl-4,5-dihydrooxazole-4-carboxylate 
• 889893-58-7 ethyl (R)-3-(4-hydroxymethyl-2-phenyl-4,5-dihydrooxazol-4-yl)propionate 
• 889893-51-0 ethyl (S)-3-(4-hydroxymethyl-2-phenyl-4,5-dihydrooxazol-4-yl)propionate 
• 889893-50-9 ethyl (S,E)-3-(4-hydroxymethyl-2-phenyl-4,5-dihydrooxazol-4-yl)acrylate 

Relevant academic research and scientific papers

Solvent-Free Microwave-Assisted Efficient Synthesis of 4,4-Disubstituted 2-Oxazolines

4,4-Disubstituted 2-oxazolines have been synthesized by a microwave-promoted solvent-free direct condensation of carboxylic acids and disubstituted β-amino alcohols in good to excellent yields. Zinc oxide is a very good solid support in cases where a Lewis acid is required. The method described herein is a very good, safe, clean, economical, and environmentally friendly alternative to the classical procedures. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.

A simple synthesis of Δ2-oxazolines, Δ2-oxazines, Δ2-thiazolines and 2-substituted benzoxazoles

Carboxylic acids react readily at 0° ← + 24°C with amino alcohols, amino mercaptans and o-aminophenols in the presence of triphenylphosphine- or tributylphosphine dichloride (generated in situ from the reaction of the phosphines with hexacholoroethane or CCl4) and triethylamine in acetonitrile to form the corresponding Δ2-oxazolines, Δ2-oxazines, Δ2-thiazolines and 2-substituted benzoxazoles in one reaction step in yields of up to 80%.

A SIMPLE SYNTHESIS OF Δ2-OXAZOLINES, Δ2-OXAZINES, Δ2-THIAZOLINES AND Δ2-IMIDAZOLINES

Carboxylic acids react with amino alcohols, amino mercaptans or diamines in the presence of triphenylphosphine, CCl4 and tert. bases to afford in 50-75percent yield the corresponding Δ2-oxazolines, Δ2-oxazines, Δ2-thiazolines and Δ2-imidazolines.