40372-09-6

Usage

Uses

Used in Pharmaceutical Industry:
O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-deoxy-6-[[(phenylMethoxy)carbonyl]amino]-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptaMine is used as an intermediate in the synthesis of various pharmaceutical compounds, such as antibiotics and antiviral drugs. Its unique structure and functional groups make it a valuable building block for the development of new therapeutic agents.
Used in Chemical Synthesis:
In the field of organic chemistry, this complex carbohydrate derivative can be used as a starting material for the synthesis of a wide range of compounds with potential applications in various industries. Its versatility in chemical reactions, such as glycosylation and amide formation, allows for the creation of novel molecules with tailored properties.
Used in Research and Development:
Due to its structural complexity and unique features, O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-deoxy-6-[[(phenylMethoxy)carbonyl]amino]-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptaMine can be employed in research and development efforts to study the properties and interactions of complex carbohydrates. This may lead to a better understanding of their role in biological systems and the development of new strategies for targeting them in therapeutic applications.

Upstream product

• 62210-73-5 N-<<(benzyloxy)carbonyl>oxy>-5-norbornene-2,3-dicarboximide 
• 1092494-97-7 N-benzyloxycarbonyloxy-5-norbornene-endo-2,3-dicarboximide 

Relevant academic research and scientific papers

Loss of individual electrostatic interactions between aminoglycoside antibiotics and resistance enzymes as an effective means to overcoming bacterial drug resistance

Aminoglycoside-modifying enzymes modify the structures of aminoglycoside antibiotics, rendering them ineffective, a process which confers resistance to the antibiotic. Electrostatic interactions (ion pairing and hydrogen bonding) are believed to be signif

Aminoglycoside-derived cationic lipids for gene transfection: Synthesis of kanamycin A derivatives

Cationic lipids are currently actively investigated as an alternative approach to recombinant viruses for gene transfer studies and gene therapy applications. Basically, they rely on the formation of lipid/DNA aggregates via electrostatic interactions between their cationic headgroup and the negatively charged DNA. The development of new amphiphilic structures should allow to shed light on their still poorly understood structure/activity relationship and thereby help to design improved vectors. It appears that aminoglycosides, which are natural polyamines known to bind to nucleic acids, provide a favourable scaffold for the synthesis of a variety of cationic lipids because of their structural features and multifunctional nature. The synthesis and full characterization of a series of lipophilic derivatives of the aminoglycoside antibiotic kanamycin A, mainly kanamycin-cholesterol conjugates, are reported herein. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.