62224-22-0Relevant articles and documents
Magnesium Bisamide-Mediated Halogen Dance of Bromothiophenes
Yamane, Yoshiki,Sunahara, Kazuhiro,Okano, Kentaro,Mori, Atsunori
supporting information, p. 1688 - 1691 (2018/03/23)
A magnesium bisamide-mediated halogen dance of bromothiophenes is described. The thienylmagnesium species generated in situ is more stable than the corresponding thienyllithium species, which was applied to trap the transient anion species with several electrophiles, such as allyl iodide, phenyl isocyanate, and tributylstannyl chloride. The utility of the magnesium bisamide-mediated halogen dance is useful in the concise synthesis of a medicinally advantageous compound via a one-pot, ester-directed halogen dance/Negishi cross coupling.
Insights into the mechanism of the site-selective sequential palladium-catalyzed cross-coupling reactions of dibromothiophenes/ dibromothiazoles and arylboronic acids. Synthesis of PPARβ/δ agonists
Pereira, Raquel,Furst, Audrey,Iglesias, Beatriz,Germain, Pierre,Gronemeyer, Hinrich,De Lera, Angel R.
, p. 4514 - 4525 (2008/09/19)
A reactivity study, aided by NMR spectroscopy, allowed a mechanistic rationale to be postulated for the palladium-catalyzed regioselective coupling of arylboronic acid (and arylstannane where feasible) at the position next to the sulfur atom in functional
SYNTHESIS OF 2-SUBSTITUTED 3,5-DIBROMOTHIOPHENES THROUGH BASE-CATALYZED HALOGEN DANCE REACTION OF 2,5-DIBROMOTHIOPHENE
Kano, Shinzo,Yuasa, Yoko,Yokomatsu, Tsutomu,Shibuya, Shiroshi
, p. 2035 - 2037 (2007/10/02)
Treatment of 2,5-dibromothiophene with LDA in THF at - 78 deg C, followed by quenching with electrophiles afforded the corresponding 2-substituted 3,5-dibromothiophenes in good yield.
