675872-43-2

Basic information

• Product Name: (3,5-dibroMothiophen-2-yl)Methanol
• Synonyms: (3,5-dibroMothiophen-2-yl)Methanol
• CAS NO: 675872-43-2
• Molecular Formula: C₅H₄Br₂OS
• Molecular Weight: 271.95766
• Mol File: 675872-43-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3,5-dibroMothiophen-2-yl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (3,5-dibroMothiophen-2-yl)Methanol(675872-43-2)
• EPA Substance Registry System: (3,5-dibroMothiophen-2-yl)Methanol(675872-43-2)

Safety Data

• Hazardous Substances Data: 675872-43-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(3,5-dibromothiophen-2-yl)methanol is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, (3,5-dibromothiophen-2-yl)methanol is utilized as a precursor in the production of agrochemicals, which can help in the development of effective pesticides and other agricultural chemicals.
Used in Polymer Production:
(3,5-dibromothiophen-2-yl)methanol is employed as a monomer or building block in the production of polymers, contributing to the creation of materials with specific properties for various applications.
Used in Organic Synthesis:
As a versatile chemical compound, (3,5-dibromothiophen-2-yl)methanol is used in organic synthesis for the creation of a wide range of organic compounds, expanding the scope of chemical research and development.

Upstream product

• 23688-07-5 3,5-dibromo-2-thiophenecarboxaldehyde 
• 62224-22-0 ethyl 3,5-dibromothiophene-2-carboxylate 
• 7311-68-4 3,5-dibromothiophene-2-carboxylic acid 

Downstream Products

• 918164-68-8 [3-bromo-5-(4-trifluoromethylphenyl)thien-2-yl]methanol 
• 918164-46-2 PdBr(P(C₆H₅)3)2C₄HSBrCH₂OH 

Relevant articles and documents

Preparation method of hydroxymethyl-substituted aromatic heterocyclic compound

The invention provides a preparation method of a hydroxymethyl-substituted aromatic heterocyclic compound, which comprises the following steps: in the presence of protective gas, dissolving aromatic heterocarboxylic acid in an aprotic solvent, adding a reducing agent in an ice bath, performing heating to room temperature, and performing reacting to obtain the hydroxymethyl-substituted aromatic heterocyclic compound. The yield of the hydroxymethyl substituted aromatic heterocyclic compound is 93% or above, the raw materials are cheap and easy to obtain, the method is simple, efficient and mildin reaction condition, and the defect that dangerous chemicals such as sodium borohydride which are prone to explosion are used in a conventional synthesis method can be overcome.

Insights into the mechanism of the site-selective sequential palladium-catalyzed cross-coupling reactions of dibromothiophenes/ dibromothiazoles and arylboronic acids. Synthesis of PPARβ/δ agonists

A reactivity study, aided by NMR spectroscopy, allowed a mechanistic rationale to be postulated for the palladium-catalyzed regioselective coupling of arylboronic acid (and arylstannane where feasible) at the position next to the sulfur atom in functional

Construction of Arene-Fused-Piperidine Motifs by Asymmetric Addition of 2-Trityloxymethylaryllithiums to Nitroalkenes: The Asymmetric Synthesis of a Dopamine D1 Full Agonist, A-86929

The straightforward methodology for the construction of chiral arene-fused-piperidine motifs using a highly enantioselective addition of 2-trityloxymethylaryllithiums to cyclic and acyclic nitroalkenes has been developed. The versatility of the process wa