62227-61-6Relevant articles and documents
Enantioselective radical alkynylation of C(sp3)-H bonds using sulfoximine as a traceless chiral auxiliary
Nagatomo, Masanori,Yoshioka, Shun,Inoue, Masayuki
, p. 120 - 123 (2015)
Enantioselective alkynylation of C(sp3)-H bonds adjacent to a nitrogen atom has been achieved using only chiral p-tolyl tert-butyldimethylsilylethynyl sulfoximine and benzophenone under photo-irradiation conditions. A twocarbon alkyne unit was chemo- and enantioselectively transferred at the nitrogen-substituted methylene to produce the optically active propargylic amines of various structures. Remarkably, the NH-unprotected sulfoximine group efficiently transmits its stereochemical information to the product and functions as a traceless chiral auxiliary.
A New Class of Redox Isomerization of N-Alkylpropargylamines into N-Alkylideneallylamines Catalyzed by a ReBr(CO)5/Amine N-oxide System
Fukumoto, Yoshiya,Okazaki, Natsuki,Chatani, Naoto
supporting information, p. 1760 - 1765 (2019/03/11)
Redox isomerization reaction wherein N-alkylpropargylamines are converted into N-alkylideneallylamines in the presence of rhenium(I) complexes as catalysts is described. Among the additives tested, certain pyridine N-oxides and tertiary amine N-oxides wer