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4-CHLORO-7-FLUORO-QUINOLINE-3-CARBONITRILE is a quinoline derivative with the molecular formula C11H5ClFN3, featuring a cyano group at the third carbon position. This chemical compound is known for its unique structure and properties, making it a valuable building block in organic synthesis and drug discovery.

622369-70-4

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622369-70-4 Usage

Uses

Used in Pharmaceutical Industry:
4-CHLORO-7-FLUORO-QUINOLINE-3-CARBONITRILE is used as an intermediate in the synthesis of pharmaceuticals for its potential applications in the development of new drugs. Its unique structure contributes to the creation of various medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, 4-CHLORO-7-FLUORO-QUINOLINE-3-CARBONITRILE serves as an intermediate in the synthesis of agrochemicals, playing a role in developing new compounds for agricultural applications.
Used in Organic Synthesis:
4-CHLORO-7-FLUORO-QUINOLINE-3-CARBONITRILE is utilized as a building block in organic synthesis, enabling the creation of a wide range of organic compounds due to its versatile chemical structure.
Used in Chemical Research:
4-CHLORO-7-FLUORO-QUINOLINE-3-CARBONITRILE is also used in the field of chemistry research, where its unique properties are explored for potential applications and to enhance understanding of chemical reactions and processes.
Used in Biochemical Research:
4-CHLORO-7-FLUORO-QUINOLINE-3-CARBONITRILE finds application in biochemical research, where it may be employed to study interactions with biological systems and develop insights into its potential biological activities.

Check Digit Verification of cas no

The CAS Registry Mumber 622369-70-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,2,2,3,6 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 622369-70:
(8*6)+(7*2)+(6*2)+(5*3)+(4*6)+(3*9)+(2*7)+(1*0)=154
154 % 10 = 4
So 622369-70-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H4ClFN2/c11-10-6(4-13)5-14-9-3-7(12)1-2-8(9)10/h1-3,5H

622369-70-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Chloro-7-fluoroquinoline-3-carbonitrile

1.2 Other means of identification

Product number -
Other names 4-chloro-3-cyano-7-fluoro quinoline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:622369-70-4 SDS

622369-70-4Relevant academic research and scientific papers

COMPOUNDS USEFUL FOR ALTERING THE LEVELS OF BILE ACIDS FOR THE TREATMENT OF DIABETES AND CARDIOMETABOLIC DISEASE

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Page/Page column 37; 38, (2018/03/09)

Described herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as Cyp8b1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for diabetes and cardiovascular disease.

Facile preparation of new 4-phenylamino-3-quinolinecarbonitrile Src kinase inhibitors via 7-fluoro intermediates: Identification of potent 7-amino analogs

Boschelli, Diane H.,Wu, Biqi,Ye, Fei,Durutlic, Haris,Golas, Jennifer M.,Lucas, Judy,Boschelli, Frank

, p. 405 - 412 (2008/09/17)

A more efficient preparation of 4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-fluoro-6-methoxy-3-quinolinecarbonitrile (2), the penultimate intermediate in the synthesis of bosutinib (1a), was developed. New 7-alkoxy-4-phenylamino-3-quinolinecarbonitrile Src

Process for the preparation of 7-substituted-3 quinolinecarbonitriles

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Page/Page column 15-16, (2010/11/30)

There is provided a process for the preparation of 7-substituted-3-quinolinecarbonitriles and intermediates useful in a process to prepare 7-substituted-3-quinolinecarbonitriles and pharmaceutically acceptable salts is described. Where 7-fluoro-4-oxo-1,4-

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