622374-87-2Relevant academic research and scientific papers
Synthesis of a new family of glycolipidic nitrones as potential antioxidant drugs for neurodegenerative disorders
Durand, Gregory,Polidori, Ange,Salles, Jean-Pierre,Pucci, Bernard
, p. 859 - 862 (2003)
This paper deals with the synthesis of a novel series of amphiphilic glycosylated spin-traps derived from α-Phenyl-N-tert-butyl nitrone (PBN) and an initial characterization of their anti-caspase-3 activity. Preliminary investigation of their anti-apoptos
Novel ampiphilic derivatives of alpha-c-phenyl-n-tert-butyl nitrone
-
Page/Page column 11-12, (2008/06/13)
Novel compounds, derivatives of α-C-phenylN-tert-butyl nitrone, a method for production and use thereof for the preparation of medicaments for the prevention or treatment of diseases related to oxidative stress.
Synthesis and Preliminary Biological Evaluations of Ionic and Nonionic Amphiphilic α-Phenyl-N-tert-butylnitrone Derivatives
Durand, Grégory,Polidori, Ange,Ouari, Olivier,Tordo, Paul,Geromel, Vanna,Rustin, Pierre,Pucci, Bernard
, p. 5230 - 5237 (2007/10/03)
In this study we report the synthesis of a series of new amphiphilic compounds derived from α-phenyl-N-tert-butylnitrone (PBN). The nitrone function was fitted into the core of the molecule between its polar and apolar goups. The polar head consisted of a
