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622389-91-7

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622389-91-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 622389-91-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,2,2,3,8 and 9 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 622389-91:
(8*6)+(7*2)+(6*2)+(5*3)+(4*8)+(3*9)+(2*9)+(1*1)=167
167 % 10 = 7
So 622389-91-7 is a valid CAS Registry Number.

622389-91-7Downstream Products

622389-91-7Relevant articles and documents

Fluorinated triazole-containing sphingosine analogues. Syntheses and in vitro evaluation as SPHK inhibitors

Escudero-Casao, Margarita,Cardona, Adrià,Beltrán-Debón, Raúl,Díaz, Yolanda,Matheu, M. Isabel,Castillón, Sergio

, p. 7230 - 7235 (2018)

Sphingosine analogues with a rigid triazole moiety in the aliphatic chain and systematic modifications in the polar head and different degrees of fluorination at the terminus of the alkylic chain were synthesized from a common alkynyl aziridine key synthon. This key synthon was obtained by enantioselective organocatalyzed aziridination and it was subsequently ring opened in a regioselective manner in acidic medium. Up to 16 sphingosine analogues were prepared in a straightforward manner. The in vitro activity of the obtained products as SPHK1 and SPHK2 inhibitors was evaluated, displaying comparable activity to that of DMS.

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