40723-80-6

Usage

Uses

Used in Pharmaceutical Industry:
1,1,1,2,2-Pentafluoro-4-Iodobutane is used as an intermediate in the production of various pharmaceuticals, contributing to the synthesis of drugs that address a range of health conditions. Its unique chemical properties make it a valuable component in the development of new medications.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, 1,1,1,2,2-Pentafluoro-4-Iodobutane serves as an intermediate, playing a crucial role in the creation of compounds used to protect crops and enhance agricultural productivity.
Used as a Solvent:
1,1,1,2,2-Pentafluoro-4-Iodobutane is utilized as a solvent in various chemical processes, providing a medium for reactions to occur. Its solvent properties are beneficial for dissolving a wide range of substances, facilitating chemical reactions in research and industrial applications.
Used as a Reagent in Organic Synthesis:
In organic synthesis, 1,1,1,2,2-Pentafluoro-4-Iodobutane functions as a reagent, participating directly in chemical reactions to form desired products. Its reactivity and stability make it suitable for use in the synthesis of complex organic molecules.
Given the potential environmental and health risks associated with 1,1,1,2,2-Pentafluoro-4-Iodobutane, it is imperative that its use is conducted with proper safety measures and regulatory compliance to ensure the well-being of both people and the environment.

InChI:InChI=1/C4H4F5I/c5-3(6,1-2-10)4(7,8)9/h1-2H2

Upstream product

• 74-85-1 ethene 
• 354-64-3 Pentafluoroethyl iodide 

Downstream Products

• 622389-91-7 (3,3,4,4,4-pentafluorobutyl)triphenylphosphonium iodide 
• 622386-91-8 C₂₄H₃₃F₅N₂O₅S 
• 939049-18-0 S-(3,3,4,4,4-pentafluorobutyl) benzenethioate 
• 639492-80-1 tert-butyl 4-({4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridyl]phenyl}sulfonyl)perhydro-2H-pyran-4-carboxylate 
• 639497-31-7 4-{4-[5-(3,3,4,4,4-pentafluorobutyl)pyrazin-2-yl]benzenesulfonyl}tetrahydropyran-4-carboxylic acid tert-butyl ester 
• 639497-06-6 tert-butyl 4-({4-[5-(3,3,4,4,4-pentafluorobutyl)(2-pyridyl)]phenyl}sulfonyl)-1-benzylpiperidine-4-carboxylate 
• 639497-55-5 1-benzyl-4-{4-[5-(3,3,4,4,4-pentafluorobutyl)pyrazin-2-yl]benzenesulfonyl}piperidine-4-carboxylic acid tert-butyl ester 
• 701271-57-0 4-{6-[4-(3,3,4,4,4-pentafluoro-butyl)-phenyl]-pyridine-3-sulfonyl}-tetrahydro-pyran-4-carboxylic acid tert-butyl ester 
• 622386-95-2 C₁₆H₂₀F₅NO₂S 
• 1197217-26-7 C₅₂H₄₅F₅N₂O₄ 
• 1604816-54-7 phenyl 5,5,6,6,6-pentafluorohexane-1-sulfonate 
• 344452-10-4 1-iodo-5,5,6,6,6-pentafluorohexane 
• 1160186-81-1 1,1,2,2,5,5,6,6-octahydroperfluoro-1-iodooctane 
• 1160186-82-2 1,1,2,2,5,5,6,6,9,9,10,10-dodecahydroperfluoro-1-iodododecane 

Relevant academic research and scientific papers

Ethylene-tetrafluoroethylene (ETFE) cotelomer iodides and their transformation to surface protection intermediates

A new class of fluorotelomers was synthesized via the cotelomerization of ethylene and tetrafluoroethylene (TFE) with 1H,1H,2H,2H-perfluoroalkyl iodides. The telomerization led to ethylene-tetrafluoroethylene (ETFE) cotelomer iodides with the incorporation of ethylene and TFE in the cotelomer chain in an alternating fashion. By controlling the reaction parameters such as total pressure, temperature, feed ratio of the monomers, initiator feed, and conversion rate, eight-carbon cotelomer iodide or higher cotelomers could be produced preferably. The ETFE cotelomer iodides were transformed to a variety of intermediates such as alcohols, azides, amines and thiols, precursors useful to make surface modification agents.

ETHYLENE-TETRAFLUOROETHYLENE CARBOXYLIC ACIDS AND SALTS

Polyfluorinated carboxylic acids and their salts containing an ethylene-tetrafluoroethylene moiety, which are useful as surfactants in a process for the dispersion polymerization of fluorinated monomer in an aqueous polymerization medium.

Copper salt-catalysed reaction of perfluoroalkyl halides with olefins

Perfluoroalkyl halides react with olefins in the presence of copper acetate and hydrazine to give 1,2-addition products.

Metallic copper catalyst for polyfluoroalkylethyl iodide production and process for producing polyfluoroalkylethyl iodide

The present invention provides a metallic copper catalyst for use in an ethylene addition reaction to polyfluoroalkyl iodides, a process for efficiently producing a polyfluoroalkylethyl iodide using such a metal copper catalyst in an ethylene addition reaction to a polyfluoroalkyl iodide, and a process for efficiently producing a polyfluoroalkylethyl iodide from a polyfluoroalkyl iodide using the same metallic copper catalyst in a telomerization reaction and a subsequent ethylene addition reaction.

Process for addition of haloalkanes to alkenes catalyzed by an organophosphite compound

A process for catalytic addition of haloalkanes to alkenes involving the step of reacting the haloalkane with the alkene in the presence of a catalyst. The catalyst is an organophosphite compound represented by the following formula: P(ORa)(ORb)(ORc), where Ra, Rb, and Rcare each an alkyl group or an aralkyl group. The haloalkane is as follows: (i) CR1R2R3R4, wherein (a) each of R1, R2, R3and R4is selected from the group consisting of a chlorine atom, a bromine atom or an iodine atom; or (b) R1is selected from the group consisting of a linear alkyl group; a halo-substituted linear alkyl group; an aralkyl group; an aralkyl group substituted with at least one of a halogen atom on the alkyl portion thereof or a halogen atom, alkyl group, alkoxy group or —CO2R10wherein R10is a C1-C4alkyl group on the aryl portion thereof; an aryl group and an aryl group substituted with at least one of a chlorine atom, a fluorine atom, an alkoxy group or a —CO2R11group, wherein R11is a C1-C4alkyl group; and R2, R3and R4are as follows: R2is an iodine atom and R3and R4are each a halogen atom except R3and R4are not each a bromine atom or R2and R3are each a bromine atom and R4is a halogen atom. The catalyzed addition of the haloalkane to the alkene proceeds without any other components present in an excess amount, by weight, of the combined amount of the haloalkane, alkene and organophosphite catalyst compound.