622864-53-3Relevant academic research and scientific papers
Palladium-catalyzed intermolecular C-2 alkenylation of indoles using oxygen as the oxidant
Yan, Zhao-Lei,Chen, Wen-Liang,Gao, Ya-Ru,Mao, Shuai,Zhang, Yan-Lei,Wang, Yong-Qiang
supporting information, p. 1085 - 1092 (2014/04/03)
A general and efficient palladium-catalyzed intermolecular direct C-2 alkenylation of indoles using oxygen as the oxidant has been developed. The reaction is of complete regio- and stereoselectivity. All products are E-isomers at the C-2-position with no Z-isomers and 3-substituted products were detected.
PROCESSES FOR PREPARING INDOLES
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Paragraph 00102, (2013/07/05)
Methods for the synthesis of an indole in provided. Methods comprise oxidizing a N-aryl imine in the presence of a palladium-based catalyst, an oxidant, and a solvent.
Palladium-catalyzed aerobic oxidative cyclization of N-aryl imines: Indole synthesis from anilines and ketones
Wei, Ye,Deb, Indubhusan,Yoshikai, Naohiko
supporting information; experimental part, p. 9098 - 9101 (2012/07/14)
We report here an operationally simple, palladium-catalyzed cyclization reaction of N-aryl imines, affording indoles via the oxidative linkage of two C-H bonds under mild conditions using molecular oxygen as the sole oxidant. The process allows quick and atom-economical assembly of indole rings from inexpensive and readily available anilines and ketones and tolerates a broad range of functional groups.
