62291-19-4

Basic information

• Product Name: 7-METHOXY-2,2-DIMETHYL-2H-CHROMENE-6-CARBALDEHYDE
• Synonyms: 7-METHOXY-2,2-DIMETHYL-2H-CHROMENE-6-CARBALDEHYDE
• CAS NO: 62291-19-4
• Molecular Formula: C₁₃H₁₄O₃
• Molecular Weight: 218.25
• Mol File: 62291-19-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-METHOXY-2,2-DIMETHYL-2H-CHROMENE-6-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-METHOXY-2,2-DIMETHYL-2H-CHROMENE-6-CARBALDEHYDE(62291-19-4)
• EPA Substance Registry System: 7-METHOXY-2,2-DIMETHYL-2H-CHROMENE-6-CARBALDEHYDE(62291-19-4)

Safety Data

• Hazardous Substances Data: 62291-19-4(Hazardous Substances Data)

Upstream product

• 17598-02-6 2,2 dimethyl 7 methoxychromene 
• 93-61-8 N-methyl-N-phenylformamide 
• 68-12-2 N,N-dimethyl-formamide 
• 18278-34-7 4-hydroxy-2-methoxybenzaldehyde 
• 79571-16-7 2-methoxy-4-(1,1-dimethyl-2-propynyloxy)benzaldehyde 

Downstream Products

• 74094-51-2 6-hydroxy-7-methoxy-2,2-dimethylchromen 
• 65383-74-6 6-Ethoxy-7-methoxy-2,2-dimethyl-2H-chromene 
• 644-06-4 precocene II 

Relevant articles and documents

Concise Synthesis of Chromene/Chromane-Type Aryne Precursors and Their Applications

The gram-scale synthesis of 5,6-, 6,7-, and 7,8-chromene/chromane-type aryne precursors and their applications in regioselective transformation to other functional derivatives is reported. Chromene/chromane-type arynes are generated under mild conditions, which can further undergo [2 + 2], [3 + 2], and [4 + 2] cycloaddition reactions, nucleophilic addition reactions, and σ-insertion reactions to produce structurally novel substituted chromenes and chromanes. The excellent regioselectivity of the reaction is facilitated by the oxygen-containing guiding groups at the ortho-position of the triple bond, which can be removed or switched to other functional groups including alkenyl, aryl, heteroaryl, and arylamino groups.

Acylation of 2,2-Dimathyl-2H-chromenes

Orientation in acylation reactions of 2,2-dimethyl-2H-chromenes was studied.Five acetylchromenes were obtained with two methods and six formylchromenes were obtained with a third method.Demethylation of four acyl-methoxy-substituted chromenes gave the corresponding acylchromenols. 2,2-Dimethyl-2H-chromene-6-carboxylic acid (anofinic acid) was also obtained by oxidation of 6-formylchromene.

SYNTHESIS OF ISOSOPHORONOL, AN ISOFLAVANONE FROM Sophora tomentosa

2,3-Dihydro-5,7-dihydroxy-3-(5-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-4H-1-benzopyran-4-one, i.e. isosophoronol (1) has been prepared, in the racemic form, by two routes both utilizing the oxidative rearangement of a chalcone with thallium(III) nitrate.