623-16-5

Usage

Uses

Used in Adhesives, Resins, and Plastics Production:
(2E)-3-(2-furyl)prop-2-enamide is used as a monomer in the synthesis of polymers for the production of adhesives, resins, and plastics. Its high reactivity and versatility contribute to the development of these materials with improved mechanical properties.
Used in Coatings Formulation:
(2E)-3-(2-furyl)prop-2-enamide is used as a cross-linking agent in the formulation of coatings. This enhances the mechanical properties and durability of the coatings, providing better performance in various applications.
Used in Paper Products Manufacturing:
(2E)-3-(2-furyl)prop-2-enamide is utilized in the manufacture of paper products, where it serves as a cross-linking agent to improve the strength and stability of the paper.
Used in Pharmaceutical Industry:
(2E)-3-(2-furyl)prop-2-enamide has applications in the pharmaceutical industry, where it may be used in the development of new drugs or as an intermediate in the synthesis of pharmaceutical compounds.
Used in Agricultural Industry:
(2E)-3-(2-furyl)prop-2-enamide is also utilized in the agricultural industry, potentially for the development of new agrochemicals or as an intermediate in the synthesis of agricultural products.
However, it is important to handle (2E)-3-(2-furyl)prop-2-enamide with caution, as it is known to be a potential irritant and sensitizer. Proper safety measures should be taken during its use and handling to minimize any adverse effects.

Upstream product

• 98-01-1 furfural 
• 683-57-8 bromo-acetic acid amide 
• 623-31-4 FAOH 

Relevant academic research and scientific papers

Highly efficient synthesis of primary amides: Via aldoximes rearrangement in water under air atmosphere catalyzed by an ionic ruthenium pincer complex

The transformation of aldoximes to primary amides has been evaluated using pincer ruthenium complexes a-c, among which the ionic Ru catalyst a proved to be the most efficient in water under air atmosphere. A variety of (hetero)arene aldoximes proceeded smoothly to afford amides in high yields with good functional group compatibilities. Furthermore, a direct synthetic route of amides from aldehydes, hydroxylamine hydrochloride and sodium carbonate was also described with broad substrates including conjugated and aliphatic aldehydes. This protocol is operationally simple and proceeds with a low catalyst loading (0.5 mol%).

Direct substitution of primary allylic amines with sulfinate salts

The NH2 group in primary allylic amines was substituted directly by sulfinate salts with excellent regio- and stereoselectivities. In the presence of 0.1 mol % [Pd(allyl)Cl]2, 0.4 mol % 1,4- bis(diphenylphosphino)butane (dppb), and excess boric acid, a range of α-unbranched primary allylic amines were smoothly substituted with sodium sulfinates in an α-selective fashion to give structurally diverse allylic sulfones in good to excellent yields with exclusive E selectivity. Replacing dppb with 1,1′-bi-2-naphthol (BINOL) allowed unsymmetric α-chiral primary allylic amines to be transformed into the corresponding allylic sulfones in good to excellent yields with excellent retention of ee. Importantly, the reaction complements known asymmetric methods in substrate scope via its unique ability to provide α-chiral allylic sulfones with high optical purity starting from unsymmetric allylic electrophiles.