62310-51-4

Upstream product

• 95477-53-5 methyl-2-<2'(R and S)-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate 
• 95477-52-4 methyl 2-<2'(R and S)-chloro-4'-oxo-3'S-α-phenoxy-α-chloromethyleneiminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate 

Relevant academic research and scientific papers

THE CHEMISTRY OF THE 6β-THIOAMIDOPENAM 1β-SULFOXIDES. THE 1,2,4-DITHIAZINEAZETIDINONES AND THIAZOLINEAZETIDINONES

6β-Thioamidopenam 1β-sulfoxides on thermolysis gave methyl 2-(3-substituted 4,5-dithia-2,7-diazabicyclooct-2-en-8-one-7-yl)-3-methyl-but-3-enoate (1,2,4-dithiazineazetidinones).The reaction of these compounds with halogenating agents is discussed.

THE CHLORINOLYSIS OF AZETIDINONE DISULFIDES

The chlorinolysis of dithiazeneazetidinones, unsym-azetidinone disulfides, and 2-chloromethylpenams, with sulfuryl chloride produce the 2--3-chloromethyl-3-chlorosulfenylbutyric acid ester isomers in which the S-isomer predominates.Treatment of this compound (R and S isomers) with pyridine results in elimination of HSCl and formation of the Z and E isomers in which the Z isomer predominates.