95477-53-5

Upstream product

• 95477-54-6 (2S,3R,6R)-3-Chloromethyl-3-methyl-7-oxo-6-phenoxycarbonylamino-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid methyl ester 
• 95477-52-4 methyl 2-<2'(R and S)-chloro-4'-oxo-3'S-α-phenoxy-α-chloromethyleneiminoazetidin-1'-yl>-3-chloromethyl-3-chlorosulfenylbutanoate 

Downstream Products

• 62310-51-4 methyl 2-<2'R-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-but-2-enoate 
• 95530-94-2 methyl 2-<2'R-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-but-2-enoate 
• 62310-51-4 methyl 2-<2'S-chloro-4'-oxo-3'S-phenoxycarbonylaminoazetidin-1'-yl>-3-chloromethyl-but-2-enoate 

Relevant academic research and scientific papers

THE CHLORINOLYSIS OF AZETIDINONE DISULFIDES

The chlorinolysis of dithiazeneazetidinones, unsym-azetidinone disulfides, and 2-chloromethylpenams, with sulfuryl chloride produce the 2--3-chloromethyl-3-chlorosulfenylbutyric acid ester isomers in which the S-isomer predominates.Treatment of this compound (R and S isomers) with pyridine results in elimination of HSCl and formation of the Z and E isomers in which the Z isomer predominates.