623143-63-5

Basic information

• Product Name: (1R-{6R-[3-(tert-butyl-dimethyl-silanyloxy)-prop-1-ynyl]-4-oxo-tetrahydro-pyran-2R-yl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester
• Synonyms: (1R-{6R-[3-(tert-butyl-dimethyl-silanyloxy)-prop-1-ynyl]-4-oxo-tetrahydro-pyran-2R-yl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester
• CAS NO: 623143-63-5
• Molecular Weight: 487.712
• Mol File: 623143-63-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R-{6R-[3-(tert-butyl-dimethyl-silanyloxy)-prop-1-ynyl]-4-oxo-tetrahydro-pyran-2R-yl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1R-{6R-[3-(tert-butyl-dimethyl-silanyloxy)-prop-1-ynyl]-4-oxo-tetrahydro-pyran-2R-yl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester(623143-63-5)
• EPA Substance Registry System: (1R-{6R-[3-(tert-butyl-dimethyl-silanyloxy)-prop-1-ynyl]-4-oxo-tetrahydro-pyran-2R-yl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester(623143-63-5)

Safety Data

• Hazardous Substances Data: 623143-63-5(Hazardous Substances Data)

Upstream product

• 77119-85-8 N-(tert-butoxycarbonyl)-D-phenylalaninal 
• 76782-82-6 tert-Butyldimethyl(prop-2-ynyloxy)silane 
• 524018-08-4 [1-(4-oxo-3,4-dihydro-2H-pyran-2-yl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester 

Downstream Products

• 623143-78-2 {1R-[6S-(3-bis(tert-butoxycarbonyl)guanidino-propyl)-4-(naphthalen-2-ylmethoxy)-tetrahydro-pyran-2R-yl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester 
• 623143-77-1 {1R-[6S-(3-hydroxy-propyl)-4-(naphthalen-2-ylmethoxy)-tetrahydro-pyran-2R-yl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester 
• 623143-76-0 (1R-{6S-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-hydroxy-tetrahydro-pyran-2R-yl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester 
• 623143-75-9 (1R-{6S-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-4-oxo-tetrahydro-pyran-2R-yl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Novel tetrahydropyran-based peptidomimetics from a bioisosteric transformation of a tripeptide. Evidence of their activity at melanocortin receptors

We have prepared novel peptidomimetics based on a 2,4,6-trisubstituted tetrahydropyran. This scaffold was constructed in an isosteric transformation using conceptual constraints imposed on a tripeptide moiety involving Oi′-Ci+1γ