623145-62-0Relevant academic research and scientific papers
Expanding the scope and orthogonality of PNA synthesis
Pothukanuri, Srinivasu,Pianowski, Zbigniew,Winssinger, Nicolas
supporting information; experimental part, p. 3141 - 3148 (2009/05/27)
Peptide nucleic acids (PNAs) hybridize to natural oligonucleotides according to Watson and Crick base-pairing rules. The robustness of PNA oligomers and ease of synthesis have made them an attractive platform to encode small or macromolecules for microarr
Azidopeptide Nucleic Acid. An Alternative Strategy for Solid-Phase Peptide Nucleic Acid (PNA) Synthesis
Debaene, Francois,Winssinger, Nicolas
, p. 4445 - 4447 (2007/10/03)
(Equation presented) A practical and efficient method for PNA synthesis using an azide group to mask the N-terminus is reported. The deprotection was carried out in 5 min, while couplings were complete within 60 min. The near neutral conditions of the pho
