623550-65-2Relevant academic research and scientific papers
Enantioselective total synthesis of (+)-ottelione A, (-)-ottelione B, (+)-3-epi-ottelione A and preliminary evaluation of their antitumor activity
Araki, Hiroshi,Inoue, Munenori,Suzuki, Takeyuki,Yamori, Takao,Kohno, Michiaki,Watanabe, Kazuhiro,Abe, Hideki,Katoh, Tadashi
, p. 9866 - 9881 (2008/09/18)
Enantioselective total synthesis of (+)-ottelione A (1) and (-)ottelione B (2), novel and potent antitumor agents from a freshwater plant, and (+)-3-epi-ottelione A (3), the earlier proposed stereostructure of 1, was efficiently achieved starting from the
Total Synthesis and Absolute Configuration of Otteliones A and B, Novel and Potent Antitumor Agents from a Freshwater Plant
Araki, Hiroshi,Inoue, Munenori,Katoh, Tadashi
, p. 3903 - 3906 (2007/10/03)
(Matrix presented) The first enantioselective total synthesis of otteliones A and B, biologically important and structurally novel natural products, has been successfully achieved. This total synthesis fully confirms the absolute configuration of these natural products.
