623553-29-7 Usage
Uses
Used in Pharmaceutical Industry:
[2-(1,3-Benzoxazol-2-yl)ethyl]amine hydrochloride is used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. Its potential biological activities, including antimicrobial, anti-inflammatory, and anticancer properties, make it a valuable compound for the development of new drugs.
Used in Organic Synthesis:
In the field of organic synthesis, [2-(1,3-Benzoxazol-2-yl)ethyl]amine hydrochloride serves as a key intermediate for the creation of other complex organic molecules. Its unique structure and reactivity contribute to the synthesis of a wide range of compounds with various applications.
Used in Antimicrobial Applications:
[2-(1,3-Benzoxazol-2-yl)ethyl]amine hydrochloride is used as an antimicrobial agent due to its potential biological activities. It can be employed in the development of new antibiotics or antimicrobial products to combat resistant bacteria and other microorganisms.
Used in Anti-inflammatory Applications:
[2-(1,3-Benzoxazol-2-yl)ethyl]amine hydrochloride is also used as an anti-inflammatory agent, leveraging its potential biological activities to reduce inflammation and alleviate pain associated with various conditions.
Used in Anticancer Applications:
[2-(1,3-Benzoxazol-2-yl)ethyl]amine hydrochloride is used in the development of anticancer drugs, targeting cancer cells and potentially inhibiting their growth and proliferation. Its incorporation into pharmaceutical formulations could lead to the creation of novel cancer treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 623553-29-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,2,3,5,5 and 3 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 623553-29:
(8*6)+(7*2)+(6*3)+(5*5)+(4*5)+(3*3)+(2*2)+(1*9)=147
147 % 10 = 7
So 623553-29-7 is a valid CAS Registry Number.
623553-29-7Relevant academic research and scientific papers
Method for synthesizing benzoxazole through microwave radiation of benzamide compound in water phase
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Paragraph 0020, (2019/03/08)
The invention discloses a method for synthesizing benzoxazole through microwave radiation of a benzamide compound in a water phase. The benzamide compound is added into the water phase under the microwave condition to be subjected to a cyclization reaction for generating the benzoxazole under the alkali condition, and the method for preparing the benzoxazole is environmentally friendly, easy and convenient to operate, safe, low in cost and efficient. Compared with the prior art, the method can be applied to a large number of functional groups, the yield is high, the number of by-products is small, and the method is easy to operate, safe, low in cost and environmentally friendly. (Please see the specifications for the formula).
Synthesis and pharmacological characterization of a new benzoxazole derivative as a potent 5-HT3 receptor agonist
Lopez-Tudanca, Pedro Luis,Labeaga, Luis,Innerarity, Ana,Alonso-Cires, Luisa,Tapia, Ines,Mosquera, Ramon,Orjales, Aurelio
, p. 2709 - 2714 (2007/10/03)
N-(2-Benzoxazol-2-yl-ethyl)-guanidine hydrochloride (10) was synthesized and pharmacologically tested. This compound showed high affinity for the 5-HT3 receptor (Ki=0.77 nM) and potently triggered the von Bezold-Jarisch reflex (BJR) in rats with an ED50=0.52 μg/kg iv and intrinsic activity next to 1 (i.a.=0.94). This stimulant effect was abolished by pretreatment with the 5-HT3 receptor antagonist granisetron and was subject to a rapid and pronounced tachyphylaxis, due to desensitization of the peripheric cardiac 5-HT3 receptor. Consequently, 10 acts as an in vivo 5-HT3 antagonist inhibiting the BJR responses evoked by submaximal doses of 5-HT with an ID50=5.8 μg/kg iv.
