623564-62-5 Usage
Description
6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carbaldehyde is a chemical compound with the molecular formula C8H8N2OS. It belongs to the class of organic compounds known as thiazines, which are heterocyclic compounds containing a five-membered ring with the formula C4H2SN. Additionally, it is classified as a pyrazole, which is a five-membered aromatic ring with the formula C3H2N2. 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carbaldehyde is a yellow liquid with a strong odor and is primarily used in chemical synthesis and research applications. Due to its potential hazardous properties, it is important to handle this chemical with caution to avoid skin or eye irritation.
Uses
Used in Chemical Synthesis:
6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carbaldehyde is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for the formation of diverse chemical products through reactions such as condensation, substitution, and cyclization.
Used in Research Applications:
In the field of research, 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carbaldehyde serves as a valuable compound for studying the properties and reactivity of thiazines and pyrazole derivatives. It can be used to investigate the mechanisms of various chemical reactions and to develop new synthetic methodologies.
Used in Pharmaceutical Industry:
6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carbaldehyde is used as a building block in the development of pharmaceutical compounds. Its unique structure and reactivity make it a promising candidate for the design of novel drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carbaldehyde can be utilized as a precursor for the synthesis of bioactive molecules with pesticidal properties. Its incorporation into agrochemical products may contribute to the development of more effective and environmentally friendly solutions for pest control.
Used in Dye and Pigment Industry:
6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carbaldehyde, due to its yellow color, can be employed as a starting material for the synthesis of dyes and pigments. Its unique chemical properties may lead to the development of new colorants with improved performance characteristics for various applications, such as textiles, plastics, and inks.
Check Digit Verification of cas no
The CAS Registry Mumber 623564-62-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,2,3,5,6 and 4 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 623564-62:
(8*6)+(7*2)+(6*3)+(5*5)+(4*6)+(3*4)+(2*6)+(1*2)=155
155 % 10 = 5
So 623564-62-5 is a valid CAS Registry Number.
623564-62-5Relevant articles and documents
Structure-activity relationship of 6-methylidene penems bearing 6,5 bicyclic heterocycles as broad-spectrum β-lactamase inhibitors: Evidence for 1,4-thiazepine intermediates with C7 R stereochemistry by computational methods
Venkatesan, Aranapakam M.,Agarwal, Atul,Abe, Takao,Ushirogochi, Hideki,Yamamura, Itsuka,Ado, Mihira,Tsuyoshi, Takasaki,Dos Santos, Osvaldo,Gu, Yansong,Sum, Fuk-Wah,Li, Zhong,Francisco, Gerry,Lin, Yang-I.,Petersen, Peter J.,Yang, Youjun,Kumagai, Toshio,Weiss, William J.,Shlaes, David M.,Knox, James R.,Mansour, Tarek S.
, p. 4623 - 4637 (2007/10/03)
The design and synthesis of a series of 6-methylidene penems containing [6,5]-fused bicycles (thiophene, imidazole, or pyrazle-fused system) as novel class A, B, and C β-lactamase inhibitors is described. These penems proved to be potent inhibitors of the TEM-1 (class A) and AmpC (class C) β-lactamases and less so against the class B metallo-β-lactamase CcrA. Their in vitro and in vivo activities in combination with piperacillin are discussed. On the basis of the crystallographic structures of a serine-bound reaction intermediate of 2 with SHV-1 (class A) and GC1 (class C) enzymes, compounds 14a-1 were designed and synthesized. Penems are proposed to form a seven-membered 1,4 thiazepine ring in both class A and C β-lactamases. The interaction energy calculation for the enzyme-bound intermediates favor the formation of the C7 R enantiomer over the S enantiomer of the 1,4-thiazepine in both β-lactamases, which is consistent with those obtained from the crystal structure of 2 with SHV-1 and GC1.
Process for preparing 6-alkylidene penem derivatives
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, (2008/06/13)
The present invention provides a process of making compounds of formula I, which are useful for the treatment of bacterial infection or disease.
PROCESS FOR PREPARING 6-ALKYLIDENE PENEM DERIVATIVES
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Page/Page column 105, (2010/02/07)
The present invention provides a process of making compounds of Formula (I), which are useful for the treatment of bacterial infection or disease.
