623564-59-0

Basic information

• Product Name: ethyl 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carboxylate
• Synonyms: ethyl 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carboxylate;6,7-Dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carboxylic acid ethyl ester
• CAS NO: 623564-59-0
• Molecular Formula: C₉H₁₂N₂O₂S
• Molecular Weight: 212.26878
• Mol File: 623564-59-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 398.428 °C at 760 mmHg
• Flash Point: 194.763 °C
• Appearance: /
• Density: 1.384 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ethyl 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carboxylate(623564-59-0)
• EPA Substance Registry System: ethyl 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carboxylate(623564-59-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 623564-59-0(Hazardous Substances Data)

Usage

General Description

Ethyl 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carboxylate is a chemical compound with the molecular formula C10H12N2O2S. It belongs to the class of pyrazolo-thiazine derivatives and is often used in pharmaceutical research for its potential biological activities. ethyl 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carboxylate exhibits structural and functional similarities to certain natural products, making it a target for drug discovery and development. Its unique structure and potential pharmacological properties make it a valuable compound for further studies in the field of medicinal chemistry and drug synthesis.

Upstream product

• 623564-58-9 3-oxo-3a,4,6,7-tetrahydro-3H-2-oxa-5-thia-1-aza-7a-azonioindenide 
• 623-47-2 propynoic acid ethyl ester 
• 718621-54-6 3-oxo-3a,4,6,7-tetrahydro-3H-2-oxa-5-thia-1-aza-7a-azonioindenide 

Downstream Products

• 623565-08-2 (5R,6RS)-6-[(RS)-acetoxy-(5,5-dioxo-4,5,6,7-tetrahydro-5λ⁶-pyrazolo[5,1-c][1,4]thiazin-2-yl)methyl]-6-bromo-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitrobenzyl ester 
• 1027013-15-5 6-[acetoxy-(6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazin-2-yl)-methyl]-6-bromo-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 623565-07-1 5,5-dioxo-4,5,6,7-tetrahydro-5λ⁶-pyrazolo[5,1-c][1,4]thiazine-2-carbaldehyde 
• 623564-62-5 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]thiazine-2-carbaldehyde 

Relevant articles and documents

MACROCYCLIC FUSED PYRRAZOLES AS MCL-1 INHIBITORS

Provided are compounds represented by Formula IA: (IA), and the pharmaceutically acceptable salts and solvates thereof, wherein R, R 1a, R 1b, L 1, L 2, L 3, X, A, B and C are as defined as set forth

Bicyclic 6-alkylidene-penems as class-D beta-lactamases inhibitors

This invention relates to certain bicyclic 6-alkylidene penems which act as a inhibitor of class-D enzymes. β-Lactamases hydrolyze β-lactam antibiotics, and as such serve as the primary cause of bacterial resistance. The compounds of the present invention when combined with β-lactam antibiotics will provide an effective treatment against life threatening bacterial infections. In accordance with the present invention there are provided compounds of general formula I or a pharmaceutically acceptable salt or in vivo hydrolyzable ester R5 thereof: wherein: One of A and B denotes hydrogen and the other an optionally substituted fused bicyclic heteroaryl group; and X═O or S.

PROCESS FOR PREPARING 6-ALKYLIDENE PENEM DERIVATIVES

The present invention provides a process of making compounds of Formula (I), which are useful for the treatment of bacterial infection or disease.