623582-47-8Relevant academic research and scientific papers
2-Isoxazolidineethanols: An NMR study of the effect of intramolecular H-bonding on the population of nitrogen invertomers and inversion process
Ali, Shaikh A.,Iman, Muhammad Z.N.,Wazeer, Mohamed I.M.,Fettouhi, Mohammed B.
, p. 482 - 490 (2008/09/21)
A series of (βR,5R)- and (βR,5S)-2,5-disubstituted isoxazolidines: 5-(substituent)-β-phenyl-2-isoxazolidineethanols, have been prepared by asymmetric nitrone cycloaddition reactions and their NMR spectra recorded over a wide range of temperatures. The spe
The stereochemistry of 1,3-dipolar cycloaddition of internally H-bonded chiral methylenenitrones
Ali, Shaikh A.,Iman, Muhammad Z.N.
, p. 9134 - 9145 (2008/02/10)
A study of diastereoselectivity in the cycloaddition reactions of a series of mono- and disubstituted alkenes with two chiral, internally H-bonded methylenenitrones has been carried out. The high degree of stereochemical control in the presence of anhydro
Synthesis of Cyclic and Acyclic β-Amino Acids via Chelation-Controlled 1,3-Dipolar Cycloaddition
Hanselmann, Roger,Zhou, Jiacheng,Ma, Philip,Confalone, Pat N.
, p. 8739 - 8741 (2007/10/03)
Isoxazolidines have been synthesized in diastereomeric excess up to 94% via a MgBr2-induced chelation-controlled 1,3-dipolar cycloaddition reaction with N-hydroxyphenylglycinol as a chiral auxiliary. The diastereomerically pure isoxazolidines were further transformed into cyclic and acyclic β-amino acid derivatives.
