623582-49-0

Basic information

• Product Name: (R)-2-((3S,5R)-3-Ethyl-5-hydroxymethyl-isoxazolidin-2-yl)-2-phenyl-ethanol
• Synonyms: (R)-2-((3S,5R)-3-Ethyl-5-hydroxymethyl-isoxazolidin-2-yl)-2-phenyl-ethanol
• CAS NO: 623582-49-0
• Molecular Weight: 251.326
• Mol File: 623582-49-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-((3S,5R)-3-Ethyl-5-hydroxymethyl-isoxazolidin-2-yl)-2-phenyl-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-((3S,5R)-3-Ethyl-5-hydroxymethyl-isoxazolidin-2-yl)-2-phenyl-ethanol(623582-49-0)
• EPA Substance Registry System: (R)-2-((3S,5R)-3-Ethyl-5-hydroxymethyl-isoxazolidin-2-yl)-2-phenyl-ethanol(623582-49-0)

Safety Data

• Hazardous Substances Data: 623582-49-0(Hazardous Substances Data)

Upstream product

• 123-38-6 propionaldehyde 
• 107-18-6 allyl alcohol 
• 321174-47-4 (R)-α-(hydroxymethyl)benzylhydroxylamine 

Downstream Products

• 183990-48-9 (S)-3-(N-tert-butoxycarbonylamino)pentanoic acid 

Relevant articles and documents

Synthesis of Cyclic and Acyclic β-Amino Acids via Chelation-Controlled 1,3-Dipolar Cycloaddition

Isoxazolidines have been synthesized in diastereomeric excess up to 94% via a MgBr2-induced chelation-controlled 1,3-dipolar cycloaddition reaction with N-hydroxyphenylglycinol as a chiral auxiliary. The diastereomerically pure isoxazolidines were further transformed into cyclic and acyclic β-amino acid derivatives.