623588-61-4Relevant academic research and scientific papers
Reversed hydroxamate-bearing thermolysin inhibitors mimic a high-energy intermediate along the enzyme-catalyzed proteolytic reaction pathway
Park, Jung Dae,Kim, Dong H.
, p. 3161 - 3166 (2003)
A series of inhibitors that bear a reversed hydroxamate moiety have been evaluated as transition state analogue inhibitors for thermolysin. A linear correlation is observed between the Ki values of these inhibitors and the kinetic parameters (K
