62359-02-8Relevant academic research and scientific papers
Intramolecular Schmidt Reaction of Vinyl Azides with Cyclic Ketones
Chen, Peng,Sun, Chu-Han,Wang, Yu,Xue, Ying,Chen, Chen,Shen, Mei-Hua,Xu, Hua-Dong
, p. 1643 - 1646 (2018)
Cyclic ketones tethered with a vinyl azide group undergo a Schmidt-hydrolysis sequence to give secondary lactams bearing a ketone side chain. Secondary lactams are obtained in a regioselective manner that is not possible in a conventional Schimdt reaction. In addition to the well-documented C-2 nucleophilicity, the N nucleophilicity of vinyl azide disclosed in this work opens a new direction for reaction invention involving vinyl azides.
TETRAHYDROINDOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS
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Page/Page column 50; 52, (2008/12/04)
The present invention is related to tetrahydroindolederivatives of Formula (I), pharmaceutical composition thereof, methods of preparation thereofand to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphateoxidase (NADPH Oxidase).
