62373-93-7

Upstream product

• 92863-41-7 1-Phenyl-butin-⁽¹⁾-al-⁽⁴⁾-diethylacetal 
• 33734-07-5 1-ethoxy-4-phenyl-1-buten-3-yne 
• 536-74-3 phenylacetylene 
• 4440-01-1 lithium phenylacetylide 
• 10229-11-5 4-phenyl-but-3-yn-1-ol 

Downstream Products

• 1372870-64-8 7-phenylhept-1-en-6-yn-3-yl 2-chloroacetate 
• 1276664-16-4 7-phenylhept-1-en-6-yn-3-ol 
• 4289-20-7 1-phenyl-4-penten-1-yne 

Relevant academic research and scientific papers

Palladium-catalyzed cascade process to construct 1,2,5-trisubstituted pyrroles

A novel palladium-catalyzed cascade allylic amination/intramolecular hydroamination/isomerization process of protected enynol 1 and primary amine 2 has been explored, which constructs the important 1,2,5-trisubstituted pyrroles. This transformation offers an alternative synthetic methodology capable of generating substituted pyrroles in a straightforward way.

Formation of 1- and 2-Alkoxyenynes in Palladium-Catalyzed Cross-Coupling of 1- and 2-Bromoalkenyl Alkyl Ethers with Alkynes

A preparative route to 1- and 2-alkoxyenynes is developed on the basis of stereoselective cross-coupling of 1- and 2-haloalkenyl alkyl ethers with terminal alkynes in the presence of palladium catalyst. Hydrolysis of 1- and 2-alkoxyenynes yields carbonyl derivatives containing a triple bond: substituted acetaldehyde and ketone, respectively.