623906-15-0Relevant academic research and scientific papers
Process for preparing 6-alkylidene penem derivatives
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, (2008/06/13)
The present invention provides a process of making compounds of formula I, which are useful for the treatment of bacterial infection or disease.
A novel, mild, and facile method to prepare 6-methylidene pe nem derivatives
Abe, Takao,Sato, Chisato,Ushirogochi, Hideki,Sato, Koichi,Takasaki, Tsuyoshi,Isoda, Takeshi,Mihira, Ado,Yamamura, Itsuki,Hayashi, Kazuhiko,Kumagai, Toshio,Tamai, Satoshi,Shiro, Motoo,Venkatesan, Aranapakam M.,Mansour, Tarek S.
, p. 5850 - 5860 (2007/10/03)
A novel and mild method was established to synthesize 6-methylidene penem compounds. This method entails a MgBr2/Et3N-promoted aldol-type condensation on 6-bromopenem 12 with an appropriately substituted aldehyde to yield the interme
