945402-14-2

Upstream product

• 623926-60-3 1-(((5S,6S,7R,8R,Z)-8,11-bis(tert-butyldimethylsilyloxy)-5,7-dimethylundeca-1,3-dien-6-yloxy)methyl)-4-methoxybenzene 
• 1026307-82-3 (2R,3R,4R,5R)-5,8-Bis-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-2,4-dimethyl-octanal 
• 623926-61-4 (4R,5R,6S,7S,Z)-6-(4-methoxybenzyloxy)-4-(tert-butyldimethylsilyloxy)-5,7-dimethylundeca-8,10-dien-1-ol 
• 252342-49-7 (2R,3S,4S)-3-hydroxy-5-(4-methoxybenzyloxy)-2,4-dimethylpentanoic acid methoxymethylamide 
• 219606-81-2 (3R,4S)-4,6-bis(tert-butyldimethylsilyloxy)-3-methylhex-1-ene 
• 1037197-61-7 (+)-tert-butyl(((2S,3S,4S)-6,6-dibromo-1-((4-methoxybenzyl)-oxy)-2,4-dimethylhex-5-en-3-yl)oxy)dimethylsilane 
• 200341-80-6 (+)-tert-butyl(((2S,3S,4S)-6,6-dibromo-1-((4-methoxybenzyl)-oxy)-2,4-dimethylhex-5-en-3-yl)oxy)dimethylsilane 
• 945402-29-9 methyl (2Z,4E)-(6R,7S)-7-(tert-butyldimethylsilyloxy)-6-methyl-9-oxo-nona-2,4-dienoate 
• 945402-05-1 (2Z,4E,6R,7S)-methyl 7-(tert-butyldimethylsilyloxy)-9-(methoxy(methyl)amino)-6-methyl-9-oxonona-2,4-dienoate 
• 945402-04-0 (E)-(4R,5S)-5,7-bis-(tert-butyl-dimethylsilyloxy)-4-methyl-hept-2-enal 
• 945402-03-9 C₂₂H₄₄O₃Si₂ 
• 945402-13-1 (2Z,4E,6R,7S,9S,10Z,12S,13R,14S,15Z,19R,20R,21S,22S,23Z)-21-(4-methoxybenzyloxy)-1,7,13,19-tetrakis(tert-butyldimethylsilyloxy)-6,12,14,20,22-pentamethylhexacosa-2,4,10,15,23,25-hexaen-9-ol 
• 945402-02-8 C₁₄H₂₇IO₂Si 
• 945402-12-0 1-(((3Z,5S,6S,7R,8R,11Z,13S,14R,15S,16Z)-8,14-bis(tert-butyldimethylsilyloxy)-17-iodo-5,7,13,15-tetramethylheptadeca-1,3,11,16-tetraen-6-yloxy)methyl)-4-methoxybenzene 

Downstream Products

• 945402-37-9 C₆₃H₁₁₄O₇Si₄ 
• 945402-38-0 (2Z,4E,6R,7S,9S,10Z,12S,13R,14S,15Z,19R,20R,21S,22S,23Z)-21-(4-methoxybenzyloxy)-7,9,13,19-tetrakis(tert-butyldimethylsilyloxy)-6,12,14,20,22-pentamethylhexacosa-2,4,10,15,23,25-hexaenoic acid 

Relevant academic research and scientific papers

Total synthesis and biological evaluation of C16 analogs of (-)-dictyostatin

The structure-activity relationship of the crucial C16 region of (-)-dictyostatin was established through total synthesis of analogs followed by detailed biological characterization. A versatile synthetic strategy was used to prepare milligram quantities