623950-03-8Relevant articles and documents
PROCESS FOR THE PREPARATION OF OPIOID MODULATORS
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Page/Page column 31, (2019/11/04)
It is described an industrially viable and advantageous process for the preparation of mixed μOR agonist/δOR antagonists (9). The invention also discloses the intermediates obtained in the process.
PROCESS FOR THE PREPARATION OF OPIOID MODULATORS
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Page/Page column 32, (2008/06/13)
The present invention is directed to novel processes for the preparation of opioid modulators (agonists and antagonists) and intermediates in their synthesis. The opioid modulators are useful for the treatment and prevention of as pain and gastrointestina
A convenient, large-scale synthesis of 4′-carboxamido N-Boc-2′,6′-dimethyl-l-phenylalanines
Cai, Chaozhong,Breslin, Henry J.,He, Wei
, p. 6836 - 6838 (2007/10/03)
A large-scale synthesis of a series of 4′-carboxamido N-Boc-2′,6′-dimethyl-l-phenylalanines is described. This method features mild reaction conditions and high chemical yields from commercially available N-Boc-2′,6′-dimethyl-l-tyrosine methyl ester.
NOVEL COMPOUNDS AS OPIOID RECEPTOR MODULATORS
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Page/Page column 37-38, (2010/02/13)
The present invention is directed to novel opioid receptor modulators of Formula (I). The invention further relates to methods for preparing such compounds, pharmaceutical compositions containing them, and their use in the treatment of disorders that may
Novel compounds as opioid receptor modulators
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Page/Page column 32, (2010/02/05)
This invention is directed towards novel compounds as opioid receptor modulators, antagonists, and agonists useful for the treatment of opioid modulated disorders such as pain and gastrointestinal disorders.