62402-19-1

Upstream product

• 150975-29-4 2-methoxy-N-((pyridin-2-yl)methylene)ethanamine 
• 1121-60-4 pyridine-2-carbaldehyde 
• 109-85-3 2-methoxyethylamine 

Downstream Products

• 1356339-50-8 2,6-bis(((2-methoxyethyl)(pyridin-2-ylmethyl)amino)methyl)-4-methylphenol 
• 1356339-52-0 2,6-bis(((2-methoxyethyl)(pyridin-2-ylmethyl)amino)methyl)-4-nitrophenol 
• 1356339-53-1 4-bromo-2,6-bis(((2-methoxyethyl)(pyridin-2-ylmethyl)amino)methyl)phenol 
• 1443518-12-4 2-(((2-methoxyethyl)(pyridine-2-ylmethyl)-amino)methyl)-4-methyl-6-(((pyridin-2-ylmethyl)(4-vinylbenzyl)-amino)methyl)phenol 
• 1443518-11-3 2-(((2-methoxyethyl)(pyridin-2-ylmethyl)-amino)methyl)-4-methyl-6-(((pyridin-2-ylmethyl)amino)methyl)-phenol 
• 1443518-13-5 2-hydroxy-3-(((2-methoxyethyl)(pyridin-2-ylmethyl)amino)methyl)-5-methylbenzaldehyde 
• 1402045-86-6 N-(2-methoxyethyl)-N-pyridin-2-ylmethylbenzamide 
• 1391424-42-2 ethyl 4-hydroxy-3,5-bis(((2-methoxyethyl)-(pyridin-2-ylmethyl)amino)methyl)benzoate 

Relevant academic research and scientific papers

Re(I) carbonyl complexes containing pyridyl-imine and amine ligands: Synthesis, characterization and their catalytic olefin epoxidation activities

Re(I) carbonyl complexes containing pyridyl-imine or amine ligands have been synthesized and crystallographically characterized. Their catalytic activity for the cis-cyclooctene epoxidation with tert-butyl hydroperoxide (TBHP) as oxidant and the oxidation of these Re(I) complexes by TBHP have been investigated.

2-ARYL IMIDAZO[1,2-A]PYRIDINE-3-ACETAMIDE DERIVATIVES, PREPARATION METHODS AND USE THEREOF

Disclosed are 2-arylimidazo[1,2-a]pyridine-3-acetamide derivatives represented by formula I, their tautomer, racemate or optical isomer, their pharmaceutically acceptable salt, or their solvates, wherein R1, R2, R3 and R4 are defined as in the specification. Preparation methods of said compounds and use of said compounds in treating and/or preventing central nervous system disease associated with TSPO functional disorder

2-Aryl Imidazo[1,2-a]Pyridine-3-Acetamide Derivatives, Preparation Methods and Uses Thereof

Disclosed are 2-arylimidazo[1,2-a]pyridine-3-acetamide derivatives represented by formula I, their tautomer, racemate or optical isomer, their pharmaceutically acceptable salt, or their solvates, wherein R1, R2, R3 and R4 are defined as in the specification. Preparation methods of said compounds and use of said compounds in treating and/or preventing central nervous system disease associated with TSPO functional disorder

The role of Zn-OR and Zn-OH nucleophiles and the influence of para-substituents in the reactions of binuclear phosphatase mimetics

Analogues of the ligand 2,2′-(2-hydroxy-5-methyl-1,3-phenylene) bis(methylene)bis((pyridin-2-ylmethyl)azanediyl)diethanol (CH3H 3L1) are described. Complexation of these analogues, 2,6-bis(((2-methoxyethyl)(pyridin-2-ylmethyl)amino)m

Cadmium(II) complexes: Mimics of organophosphate pesticide degrading enzymes and metallo-β-lactamases

Figure Persented: Cadmium(II) complexes of ethyl 4-hydroxy-3,5-bis(((2- hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)benzoate (CO2EtH 3L1) and ethyl 4-hydroxy-3,5-bis(((2-methoxyethyl)(pyridin-2- ylmethyl)amino)methyl)benzoate (COs

Modification and optimization of the bis-picolylamide-based relay protection for carboxylic acids to be cleaved by unusual complexation with Cu2+ salts

A simple modification of our recently published protection scheme for carboxylic acids as amides resulted in a new protecting group with significantly improved properties. It requires shorter reaction times for deprotection and allows us to replace Cu(OTf)2 by CuCl2, indicating at the same time the importance of the nature of the anion of the Cu2+ source. Since the new scheme fulfills all criteria required for an ideal protection group it should find widespread application in synthetic organic chemistry.

Iron(III) complexes of N2O and N3O donor ligands as functional models for catechol dioxygenase enzymes: Ether oxygen coordination tunes the regioselectivity and reactivity

A series of mononuclear iron(iii) complexes of the type [Fe(L)Cl 3], where L is a systematically modified N2O or N 3O ligand with a methoxyethyl/tetrahydrofuryl ether oxygen donor atom, have been isolated and studied as models for catechol dioxygenases. The X-ray crystal structures of [Fe(L2)Cl3] 2, [Fe(L6)Cl3] 6, [Fe(L5)(TCC)Cl] 5a, where H2TCC = tetrachlorocatechol, [Fe(L6)(TCC)Br] 6a, and the μ-oxo dimer [{Fe(L6)Cl}2O](ClO 4)26b have been successfully determined. In [Fe(L2)Cl 3] 2 the N2O ligand is facially coordinated to iron(iii) through the pyridine and secondary amine nitrogen atoms and the tetrahydrofuryl oxygen atom. In [Fe(L6)Cl3] 6, [Fe(L5)(TCC)Cl] 5a and [Fe(L6)(TCC)Br] 6a the N3O donor ligands L5 and L6 act as a tridentate N3 donor ligand coordinated through two pyridine and one secondary amine nitrogen atoms, whereas the ether oxygen is not coordinated. The spectral and electrochemical properties of the adducts [Fe(L)(DBC)Cl] of 1-8, where H2DBC = 3,5-di-tert-butylcatechol, in DMF and their solvated adduct species [Fe(L)(DBC)(Sol)]+, where Sol = DMF/H2O, generated in situ in dichloromethane, respectively, have been investigated. The product analysis demonstrates that the adducts [Fe(L)(DBC)Cl] effect cleavage of catechol in the presence of O2 in DMF to give mainly the intradiol (I) product with a small amount of the extradiol (E) product (E/I, 0.2:1-0.7:1). Interestingly, the solvated species [Fe(L)(DBC)(Sol)]+ derived from 1-4 cleave H2DBC to provide mainly the extradiol cleavage products with lower amounts of intradiol products (E/I, 2.3:1-4.3:1) in dichloromethane. In contrast, the solvated species [Fe(L)(DBC)(Sol)]+ derived from 5-8 cleave H2DBC to provide both extradiol and intradiol products (E/I, 0.6:1-2.3:1) due to the involvement of the ether oxygen donor of the methoxyethyl/tetrahydrofuryl arm in the coordination to iron(iii) upon removal of a chloride ion. The Royal Society of Chemistry 2011.